Entity Details

Name MORC2
ID Q9Y6X9
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1MORC2Thr717
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PSPKVIKtPVVKKTEphosphorylation
down-regulates quantity by destabilization		36967563SIGNOR-277837
CDK1MORC2Thr733
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PIKLSPAtPSRKRSVphosphorylation
down-regulates quantity by destabilization		36967563SIGNOR-277838
PAK1MORC2Ser739
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ATPSRKRsVAVSDEEphosphorylation
up-regulates activity		25888627SIGNOR-273714
PAK1MORC2Ser739
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ATPSRKRsVAVSDEEphosphorylation
up-regulates activity		23260667SIGNOR-278414
PRKACAMORC2Thr582LEALQKTtPIRSQADphosphorylation
up-regulates quantity by stabilization		32401166SIGNOR-273781
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
MORC2
PThr717		phosphorylation
down-regulates
⊣		MORC236967563SIGNOR-277837
CDK1phosphorylation
up-regulates
→
MORC2
PThr733		phosphorylation
down-regulates
⊣		MORC236967563SIGNOR-277838
PAK1phosphorylation
up-regulates
→
MORC2
PSer739		phosphorylation
up-regulates
→		MORC225888627SIGNOR-273714
PAK1phosphorylation
up-regulates
→
MORC2
PSer739		phosphorylation
up-regulates
→		MORC223260667SIGNOR-278414
PRKACAphosphorylation
up-regulates
→
MORC2
PThr582		phosphorylation
up-regulates
→		MORC232401166SIGNOR-273781
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MORC2SIGNOR-277837
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MORC2SIGNOR-277838
PAK1phosphorylation
→
up-regulates activity 		MORC2SIGNOR-273714
PAK1phosphorylation
→
up-regulates activity 		MORC2SIGNOR-278414
PRKACAphosphorylation
→
up-regulates quantity by stabilization 		MORC2SIGNOR-273781