| Name | PP2Ca_R1A_Bd |
| ID | SIGNOR-C133 |
| Role | phosphatase |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PP2Ca_R1A_Bd | PDPK1 | – | dephosphorylation down-regulates activity | 21075311 | SIGNOR-243515 | |
| PP2Ca_R1A_Bd | AR | Ser83 | QQQQQETsPRQQQQQ | dephosphorylation down-regulates activity | 27858941 | SIGNOR-254759 |
| PP2Ca_R1A_Bd | GSK3B | Ser9 | SGRPRTTsFAESCKP | dephosphorylation up-regulates activity | 20080667 | SIGNOR-254754 |
| PP2Ca_R1A_Bd | MAP3K5 | Ser966 | NEYLRSIsLPVPVLV | dephosphorylation up-regulates activity | 27858941 | SIGNOR-254756 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PP2Ca_R1A_Bd | dephosphorylation down-regulates ⊣ | AR PSer83 | dephosphorylation up-regulates → | AR | 27858941 | SIGNOR-254759 |
| PP2Ca_R1A_Bd | dephosphorylation down-regulates ⊣ | GSK3B PSer9 | dephosphorylation down-regulates ⊣ | GSK3B | 20080667 | SIGNOR-254754 |
| PP2Ca_R1A_Bd | dephosphorylation down-regulates ⊣ | MAP3K5 PSer966 | dephosphorylation down-regulates ⊣ | MAP3K5 | 27858941 | SIGNOR-254756 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PP2Ca_R1A_Bd | dephosphorylation → down-regulates activity | PDPK1 | SIGNOR-243515 |
| PP2Ca_R1A_Bd | dephosphorylation → down-regulates activity | AR | SIGNOR-254759 |
| PP2Ca_R1A_Bd | dephosphorylation → up-regulates activity | GSK3B | SIGNOR-254754 |
| PP2Ca_R1A_Bd | dephosphorylation → up-regulates activity | MAP3K5 | SIGNOR-254756 |