Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAP3K14	IKK-complex	–		phosphorylation up-regulates	9520446	SIGNOR-217433
SRC	IKK-complex	–		phosphorylation up-regulates	12707358	SIGNOR-217442
AKT	IKK-complex	–		phosphorylation up-regulates	19609947	SIGNOR-244281
IKK-complex	IKK-complex	–		phosphorylation down-regulates	10195894	SIGNOR-216373
PRKAA2	IKK-complex	–		phosphorylation up-regulates	21673972	SIGNOR-217457
MAP3K7	IKK-complex	–		phosphorylation up-regulates activity	21232017	SIGNOR-209759
AKT1	IKK-complex	–		phosphorylation up-regulates	19609947	SIGNOR-217460
MAP3K7	IKK-complex	–		phosphorylation up-regulates	11460167	SIGNOR-217445
MAP3K7	IKK-complex	–		phosphorylation up-regulates activity	21133840	SIGNOR-256024
SRC	IKK-complex	–		phosphorylation up-regulates	12645577	SIGNOR-217439
AKT2	IKK-complex	–		phosphorylation up-regulates	19609947	SIGNOR-217463
AKT3	IKK-complex	–		phosphorylation up-regulates	19609947	SIGNOR-217466

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAP3K14	phosphorylation → up-regulates	IKK-complex	SIGNOR-217433
SRC	phosphorylation → up-regulates	IKK-complex	SIGNOR-217442
AKT	phosphorylation → up-regulates	IKK-complex	SIGNOR-244281
IKK-complex	phosphorylation down-regulates	IKK-complex	SIGNOR-216373
PRKAA2	phosphorylation → up-regulates	IKK-complex	SIGNOR-217457
MAP3K7	phosphorylation → up-regulates activity	IKK-complex	SIGNOR-209759
AKT1	phosphorylation → up-regulates	IKK-complex	SIGNOR-217460
MAP3K7	phosphorylation → up-regulates	IKK-complex	SIGNOR-217445
MAP3K7	phosphorylation → up-regulates activity	IKK-complex	SIGNOR-256024
SRC	phosphorylation → up-regulates	IKK-complex	SIGNOR-217439
AKT2	phosphorylation → up-regulates	IKK-complex	SIGNOR-217463
AKT3	phosphorylation → up-regulates	IKK-complex	SIGNOR-217466