| Name | AMPK |
| ID | SIGNOR-C15 |
| Role | kinase |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | CRY1 | Ser71 | ANLRKLNsRLFVIRG | phosphorylation down-regulates quantity by destabilization | 19833968 | SIGNOR-268046 |
| AMPK | RAF1 | Ser259 | SQRQRSTsTPNVHMV | phosphorylation down-regulates | 11971957 | SIGNOR-216523 |
| AMPK | INSR | – | phosphorylation up-regulates | 22207502 | SIGNOR-216619 | |
| AMPK | mTORC1 | – | phosphorylation down-regulates activity | 20083114 | SIGNOR-216422 | |
| AMPK | NEDD4L | Ser795 | VDLKPNGsEIMVTNE | phosphorylation up-regulates activity | 21501591 | SIGNOR-277858 |
| AMPK | DNMT1 | Ser714 | DNIPEMPsPKKMHQG | phosphorylation down-regulates activity | 28143904 | SIGNOR-264788 |
| AMPK | HNF4A | Ser303 | DPDAKGLsDPGKIKR | phosphorylation down-regulates | 12740371 | SIGNOR-216511 |
| AMPK | HDAC5 | Ser259 | FPLRKTAsEPNLKVR | phosphorylation down-regulates | 21892142 | SIGNOR-216596 |
| AMPK | FOXO3 | Ser626 | SLECDMEsIIRSELM | phosphorylation up-regulates activity | 17711846 | SIGNOR-249688 |
| AMPK | EPM2A | – | phosphorylation up-regulates activity | 18029386 | SIGNOR-271730 | |
| AMPK | CRTC1 | – | phosphorylation down-regulates | 21331044 | SIGNOR-216529 | |
| AMPK | MAPT | Ser396 | DDKKAKTsTRSSAKT | phosphorylation down-regulates activity | 21204788 | SIGNOR-273930 |
| AMPK | RBBP7 | Ser314 | LKLHTFEsHKDEIFQ | phosphorylation up-regulates activity | 28143904 | SIGNOR-264789 |
| AMPK | CTH | Ser346 | ESLGGFEsLAELPAI | phosphorylation up-regulates activity | 37922764 | SIGNOR-277808 |
| AMPK | HDAC7 | Ser155 | FPLRKTVsEPNLKLR | phosphorylation down-regulates | 21892142 | SIGNOR-216554 |
| AMPK | TSC1 | – | phosphorylation up-regulates | 14651849 | SIGNOR-216441 | |
| AMPK | ULK1 | Ser638 | FDFPKTPsSQNLLAL | phosphorylation up-regulates | 19584320 | SIGNOR-216499 |
| AMPK | CRTC2 | Ser171 | SALNRTSsDSALHTS | phosphorylation down-regulates | 20577053 | SIGNOR-216576 |
| AMPK | ULK1 | Ser638 | FDFPKTPsSQNLLAL | phosphorylation up-regulates | 21205641 | SIGNOR-216461 |
| AMPK | FOXO3 | Thr179 | SSPDKRLtLSQIYEW | phosphorylation up-regulates activity | 17711846 | SIGNOR-274094 |
| AMPK | TXNIP | Ser308 | GLSSRTSsMASRTSS | phosphorylation down-regulates quantity by destabilization | 23453806 | SIGNOR-276489 |
| AMPK | TET2 | – | phosphorylation up-regulates activity | 31900833 | SIGNOR-260097 | |
| AMPK | ULK1 | Ser317 | SHLASPPsLGEMQQL | phosphorylation up-regulates | 21205641 | SIGNOR-216453 |
| AMPK | CRY1 | Ser71 | ANLRKLNsRLFVIRG | phosphorylation down-regulates | 21892142 | SIGNOR-216546 |
| AMPK | GYS1 | Ser8 | MPLNRTLsMSSLPGL | phosphorylation down-regulates activity | 22233421 | SIGNOR-263102 |
| AMPK | HNF4A | Ser303 | DPDAKGLsDPGKIKR | phosphorylation down-regulates activity | 12740371 | SIGNOR-263106 |
| AMPK | PPP1R12C | Ser452 | AGLQRSAsSSWLEGT | phosphorylation down-regulates | 22137581 | SIGNOR-216600 |
| AMPK | FOXO3 | Ser555 | RALSNSVsNMGLSES | phosphorylation up-regulates activity | 17711846 | SIGNOR-249682 |
| AMPK | CCNY | Ser326 | SARKRSAsADNLTLP | phosphorylation up-regulates activity | 32723157 | SIGNOR-273001 |
| AMPK | NR2C2 | Ser351 | HVISRDQsTPIIEVE | phosphorylation down-regulates | 21478464 | SIGNOR-216537 |
| AMPK | GLI1 | Ser408 | GPLPRAPsISTVEPK | phosphorylation down-regulates quantity by destabilization | 26190112 | SIGNOR-253541 |
| AMPK | PFKFB2 | Ser466 | PVRMRRNsFTPLSSS | phosphorylation up-regulates activity | 20640476 | SIGNOR-209947 |
| AMPK | RPTOR | Ser792 | LTQSAPAsPTNKGVH | phosphorylation down-regulates | 18439900 | SIGNOR-263044 |
| AMPK | TSC | – | phosphorylation up-regulates activity | 16959574 | SIGNOR-217749 | |
| AMPK | HAT1 | Ser190 | MWFIETAsFIDVDDE | phosphorylation up-regulates activity | 28143904 | SIGNOR-264787 |
| AMPK | VASP | Thr278 | LARRRKAtQVGEKTP | phosphorylation down-regulates | 17082196 | SIGNOR-216515 |
| AMPK | PPP1R3C | Ser33 | MRLCLAHsPPVKSFL | phosphorylation down-regulates quantity by destabilization | 19171932 | SIGNOR-276237 |
| AMPK | FOXO | Ser626 | SLECDMEsIIRSELM | phosphorylation up-regulates activity | 17711846 | SIGNOR-252884 |
| AMPK | PPP1R3C | Ser33 | MRLCLAHsPPVKSFL | phosphorylation down-regulates quantity by destabilization | 19171932 | SIGNOR-273739 |
| AMPK | CDC27 | Ser379 | NALPRRSsRLFTSDS | phosphorylation unknown | 22137581 | SIGNOR-216434 |
| AMPK | CRY1 | Ser280 | YKKVKKNsSPPLSLY | phosphorylation down-regulates quantity by destabilization | 19833968 | SIGNOR-268047 |
| AMPK | SCN5A | Thr101 | IVLNKGKtIFRFSAT | phosphorylation up-regulates activity | 33410863 | SIGNOR-275769 |
| AMPK | LIPE | Ser855 | EPMRRSVsEAALAQP | phosphorylation down-regulates | 9636039 | SIGNOR-216507 |
| AMPK | FOXO3 | Ser555 | RALSNSVsNMGLSES | phosphorylation up-regulates activity | 17711846 | SIGNOR-274093 |
| AMPK | SLC12A2 | Ser77 | RPLGPTPsQSRFQVD | phosphorylation down-regulates activity | 24702155 | SIGNOR-276630 |
| AMPK | EPM2A | Ser25 | PELLVVGsRPELGRW | phosphorylation up-regulates activity | 21728993 | SIGNOR-277830 |
| AMPK | WDR45 | – | phosphorylation up-regulates activity | 28561066 | SIGNOR-268480 | |
| AMPK | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates | 15866171 | SIGNOR-216475 |
| AMPK | AMPK | – | phosphorylation up-regulates activity | 17728241 | SIGNOR-216411 | |
| AMPK | FH | Ser75 | YGAQTVRsTMNFKIG | phosphorylation up-regulates activity | 28628081 | SIGNOR-266313 |
| AMPK | HDAC5 | Ser498 | RPLSRTQsSPLPQSP | phosphorylation down-regulates | 21892142 | SIGNOR-216550 |
| AMPK | CFTR | Ser737 | EPLERRLsLVPDSEQ | phosphorylation down-regulates activity | 19095655 | SIGNOR-250350 |
| AMPK | MAPT | Ser262 | NVKSKIGsTENLKHQ | phosphorylation down-regulates activity | 21204788 | SIGNOR-273928 |
| AMPK | mTORC1 | – | phosphorylation down-regulates activity | 23863160 | SIGNOR-209862 | |
| AMPK | YBX2 | Thr115 | GFINRNDtKEDVFVH | phosphorylation up-regulates quantity by stabilization | 37860762 | SIGNOR-277868 |
| AMPK | FOXO | – | phosphorylation up-regulates | 17900900 | SIGNOR-252886 | |
| AMPK | MAPT | Thr231 | KKVAVVRtPPKSPSS | phosphorylation down-regulates activity | 21204788 | SIGNOR-273927 |
| AMPK | MLXIPL | – | phosphorylation down-regulates | 21892142 | SIGNOR-216561 | |
| AMPK | NOS3 | Ser1177 | TSRIRTQsFSLQERQ | phosphorylation up-regulates | 18303014 | SIGNOR-216627 |
| AMPK | PPARGC1A | Ser539 | SLFNVSPsCSSFNSP | phosphorylation up-regulates | 17609368 | SIGNOR-216647 |
| AMPK | CHKA | Ser279 | KKLHKLLsYNLPLEL | phosphorylation up-regulates activity | 34929314 | SIGNOR-267647 |
| AMPK | ARMC10 | Ser45 | LGIRSSKsAGALEEG | phosphorylation up-regulates activity | 30631047 | SIGNOR-266413 |
| AMPK | KLC2 | Ser582 | PRMKRASsLNFLNKS | phosphorylation up-regulates | 21725060 | SIGNOR-216468 |
| AMPK | PRPS1 | Ser180 | GGAKRVTsIADRLNV | phosphorylation down-regulates activity | 29074724 | SIGNOR-265730 |
| AMPK | MLXIPL | Ser556 | LLRSPGsPQETVPE | phosphorylation down-regulates | 11724780 | SIGNOR-216526 |
| AMPK | FOXO | Ser399 | DNITLPPsQPSPTGG | phosphorylation up-regulates activity | 17711846 | SIGNOR-252880 |
| AMPK | mTORC1 | – | phosphorylation down-regulates activity | 21460634 | SIGNOR-216418 | |
| AMPK | GAPDH | Ser122 | GAKRVIIsAPSADAP | phosphorylation up-regulates activity | 26626483 | SIGNOR-267578 |
| AMPK | NOS3 | Thr495 | TGITRKKtFKEVANA | phosphorylation down-regulates activity | 24379783 | SIGNOR-251618 |
| AMPK | KPNA2 | Ser105 | QAARKLLsREKQPPI | phosphorylation up-regulates | 15342649 | SIGNOR-216449 |
| AMPK | PIKFYVE | Ser307 | PARNRSAsITNLSLD | phosphorylation up-regulates activity | 23905686 | SIGNOR-263031 |
| AMPK | NEDD4L | Ser795 | VDLKPNGsEIMVTNE | phosphorylation up-regulates activity | 21501591 | SIGNOR-276326 |
| AMPK | RB1 | Ser811 | IYISPLKsPYKISEG | phosphorylation unknown | 19217427 | SIGNOR-216635 |
| AMPK | FOXO3 | Ser413 | GLMQRSSsFPYTTKG | phosphorylation up-regulates activity | 17711846 | SIGNOR-274098 |
| AMPK | PRPS2 | Ser180 | GGAKRVTsIADRLNV | phosphorylation down-regulates activity | 29074724 | SIGNOR-265732 |
| AMPK | ACACA | Ser80 | LHIRSSMsGLHLVKQ | phosphorylation down-regulates | 12015362 | SIGNOR-216655 |
| AMPK | ZNF692 | Ser470 | VAAHRSKsHPALLLA | phosphorylation down-regulates | 17097062 | SIGNOR-216519 |
| AMPK | GLI1 | Thr1074 | QRGSSGHtPPPSGPP | phosphorylation down-regulates quantity by destabilization | 26190112 | SIGNOR-253543 |
| AMPK | SLC9A3 | Ser563 | LAFIRSPsTDNVVNV | phosphorylation down-regulates activity | 38047302 | SIGNOR-277848 |
| AMPK | YAP1 | Ser94 | RLRKLPDsFFKPPEP | phosphorylation down-regulates activity | 25751140 | SIGNOR-277638 |
| AMPK | MFF | Ser155 | GRLKRERsMSENAVR | phosphorylation up-regulates activity | 26816379 | SIGNOR-245948 |
| AMPK | PDHA1 | Ser314 | IQEVRSKsDPIMLLK | phosphorylation up-regulates activity | 33022274 | SIGNOR-277894 |
| AMPK | FOXO3 | Ser413 | GLMQRSSsFPYTTKG | phosphorylation up-regulates activity | 17711846 | SIGNOR-249678 |
| AMPK | MFF | Ser172 | GQLVRNDsLWHRSDS | phosphorylation up-regulates activity | 26816379 | SIGNOR-249655 |
| AMPK | Gbeta | – | phosphorylation up-regulates | 20647423 | SIGNOR-216471 | |
| AMPK | SREBF1 | – | phosphorylation down-regulates | 21892142 | SIGNOR-216564 | |
| AMPK | ACSS2 | Ser659 | PGLPKTRsGKIMRRV | phosphorylation up-regulates activity | 28820290 | SIGNOR-271823 |
| AMPK | MAPT | Ser352 | PRHLSNVsSTGSIDM | phosphorylation down-regulates activity | 21204788 | SIGNOR-273929 |
| AMPK | CTBP1 | Ser158 | REGTRVQsVEQIREV | phosphorylation down-regulates | 23291169 | SIGNOR-216604 |
| AMPK | FOXO3 | – | phosphorylation up-regulates activity | 17900900 | SIGNOR-216481 | |
| AMPK | FOXO | – | phosphorylation up-regulates activity | 17900900 | SIGNOR-252889 | |
| AMPK | MAPT | Ser214 | GGKERPGsKEEVDED | phosphorylation down-regulates activity | 21204788 | SIGNOR-273926 |
| AMPK | KCNA5 | Ser592 | KCNVKAKsNVDLRRS | phosphorylation down-regulates activity | 30279167 | SIGNOR-273735 |
| AMPK | PAQR3 | Thr32 | PRGIRLYtYEQIPGS | phosphorylation up-regulates activity | 26834238 | SIGNOR-273737 |
| AMPK | PLD1 | Ser505 | GSVKRVTsGPSLGSL | phosphorylation up-regulates | 20231899 | SIGNOR-216643 |
| AMPK | HIPK2 | Ser121 | LMRRSTVsLLDTYQK | phosphorylation down-regulates activity | 23871434 | SIGNOR-275483 |
| AMPK | MAPT | Ser420 | KHPTPGSsDPLIQPS | phosphorylation down-regulates activity | 21204788 | SIGNOR-273931 |
| AMPK | AMPK | – | phosphorylation unknown | 11171104 | SIGNOR-216415 | |
| AMPK | GBF1 | Thr1337 | GKIHRSAtDADVVNS | phosphorylation down-regulates | 18063581 | SIGNOR-216588 |
| AMPK | PPARGC1A | Thr178 | NHNHRIRtNPAIVKT | phosphorylation up-regulates activity | 20640476 | SIGNOR-209936 |
| AMPK | BAIAP2 | Ser366 | KTLPRSSsMAAGLER | phosphorylation down-regulates | 22137581 | SIGNOR-216608 |
| AMPK | GYS2 | Ser8 | MLRGRSLsVTSLGGL | phosphorylation down-regulates activity | 22233421 | SIGNOR-263101 |
| AMPK | HDAC7 | Ser358 | WPLSRTRsEPLPPSA | phosphorylation down-regulates | 21892142 | SIGNOR-216558 |
| AMPK | FOXO3 | Thr179 | SSPDKRLtLSQIYEW | phosphorylation up-regulates activity | 17711846 | SIGNOR-238813 |
| AMPK | FOXO3 | Ser626 | SLECDMEsIIRSELM | phosphorylation up-regulates activity | 17711846 | SIGNOR-274097 |
| AMPK | SREBF1 | Ser396 | TAVHKSKsLKDLVSA | phosphorylation down-regulates | 21459323 | SIGNOR-216533 |
| AMPK | CTH | Thr355 | AELPAIMtHASVLKN | phosphorylation up-regulates activity | 37922764 | SIGNOR-277793 |
| AMPK | CTH | Thr355 | AELPAIMtHASVLKN | phosphorylation up-regulates activity | 37922764 | SIGNOR-277807 |
| AMPK | mTORC1 | – | phosphorylation down-regulates activity | 18439900 | SIGNOR-216430 | |
| AMPK | FOXO | Ser413 | GLMQRSSsFPYTTKG | phosphorylation up-regulates activity | 17711846 | SIGNOR-252881 |
| AMPK | CFTR | Ser768 | LQARRRQsVLNLMTH | phosphorylation down-regulates activity | 19095655 | SIGNOR-72708 |
| AMPK | CTH | Ser346 | ESLGGFEsLAELPAI | phosphorylation up-regulates activity | 37922764 | SIGNOR-277794 |
| AMPK | SIRT7 | Thr153 | TLTHMSItRLHEQKL | phosphorylation down-regulates quantity by destabilization | 27511885 | SIGNOR-275865 |
| AMPK | TET2 | Ser99 | GGIKRTVsEPSLSGLL | phosphorylation up-regulates quantity by stabilization | 30022161 | SIGNOR-256135 |
| AMPK | TBC1D1 | Ser237 | RPMRKSFsQPGLRSL | phosphorylation down-regulates | 17995453 | SIGNOR-216631 |
| AMPK | ULK1 | – | phosphorylation up-regulates | 21460634 | SIGNOR-216464 | |
| AMPK | HIPK2 | Thr119 | HNLMRRStVSLLDTY | phosphorylation down-regulates activity | 23871434 | SIGNOR-275482 |
| AMPK | CRTC2 | Ser170 | PSALNRTsSDSALHT | phosphorylation down-regulates | 21892142 | SIGNOR-216541 |
| AMPK | HIPK2 | Thr1116 | AALGSTGtVAHLVAS | phosphorylation down-regulates activity | 23871434 | SIGNOR-275484 |
| AMPK | ARMC10 | Ser45 | LGIRSSKsAGALEEG | phosphorylation up-regulates activity | 30631047 | SIGNOR-277806 |
| AMPK | SLC12A1 | Ser122 | YRNTGSIsGPKVNRP | phosphorylation up-regulates activity | 17341212 | SIGNOR-263103 |
| AMPK | ALDH2 | Thr356 | GNPFDSKtEQGPQVD | phosphorylation up-regulates activity | 30375985 | SIGNOR-271862 |
| AMPK | CSNK1E | Ser389 | RGAPANVsSSDLTGR | phosphorylation up-regulates activity | 17525164 | SIGNOR-276064 |
| AMPK | FOXO1 | – | phosphorylation up-regulates | 18394876 | SIGNOR-216478 | |
| AMPK | PDHA1 | Ser295 | RYHGHSMsDPGVSYR | phosphorylation up-regulates activity | 33022274 | SIGNOR-276835 |
| AMPK | GLI1 | Ser102 | LQTVIRTsPSSLVAF | phosphorylation down-regulates quantity by destabilization | 26190112 | SIGNOR-253542 |
| AMPK | FOXO | Ser588 | QTLSDSLsGSSLYST | phosphorylation up-regulates activity | 17711846 | SIGNOR-252883 |
| AMPK | MTOR | Ser1261 | PMKKLHVsTINLQKA | phosphorylation up-regulates activity | 31186373 | SIGNOR-262535 |
| AMPK | PPARGC1A | Thr178 | NHNHRIRtNPAIVKT | phosphorylation up-regulates | 17609368 | SIGNOR-216651 |
| AMPK | PRKAA1 | Ser486 | DDEITEAKsGTATPQRS | phosphorylation down-regulates activity | 17023420 | SIGNOR-256113 |
| AMPK | ARMC10 | Ser45 | LGIRSSKsAGALEEG | phosphorylation up-regulates activity | 30631047 | SIGNOR-277792 |
| AMPK | PPARGC1A | Thr178 | NHNHRIRtNPAIVKT | phosphorylation up-regulates activity | 17609368 | SIGNOR-228642 |
| AMPK | BAIAP2 | Ser366 | KTLPRSSsMAAGLER | phosphorylation down-regulates | 19933840 | SIGNOR-216572 |
| AMPK | FOXO3 | Ser588 | QTLSDSLsGSSLYST | phosphorylation up-regulates activity | 17711846 | SIGNOR-274096 |
| AMPK | GLI1 | Ser408 | GPLPRAPsISTVEPK | phosphorylation down-regulates quantity by destabilization | 26843621 | SIGNOR-253540 |
| AMPK | PPARGC1A | Ser539 | SLFNVSPsCSSFNSP | phosphorylation up-regulates activity | 20640476 | SIGNOR-209940 |
| AMPK | PFKFB2 | Ser466 | PVRMRRNsFTPLSSSN | phosphorylation up-regulates activity | 11069105 | SIGNOR-260011 |
| AMPK | NOS3 | Ser1177 | TSRIRTQsFSLQERQ | phosphorylation up-regulates | 11729179 | SIGNOR-216445 |
| AMPK | FOXO3 | Ser399 | DNITLPPsQPSPTGG | phosphorylation up-regulates activity | 17711846 | SIGNOR-274095 |
| AMPK | PAK2 | Ser20 | APPVRMSsTIFSTGG | phosphorylation unknown | 22137581 | SIGNOR-216612 |
| AMPK | TSC2 | Ser1387 | QPLSKSSsSPELQTL | phosphorylation up-regulates | 16959574 | SIGNOR-216438 |
| AMPK | RPTOR | Ser722 | PRLRSVSsYGNIRAV | phosphorylation down-regulates | 18439900 | SIGNOR-263046 |
| AMPK | TSC1 | – | phosphorylation up-regulates | 19584320 | SIGNOR-216487 | |
| AMPK | FOXO4 | – | phosphorylation up-regulates | 17900900 | SIGNOR-216484 | |
| AMPK | ACACA | Ser80 | LHIRSSMsGLHLVKQ | phosphorylation down-regulates activity | 29899443 | SIGNOR-267475 |
| AMPK | ULK1 | Ser556 | GLGCRLHsAPNLSDL | phosphorylation up-regulates | 19584320 | SIGNOR-216495 |
| AMPK | HDAC4 | – | phosphorylation down-regulates | 21565617 | SIGNOR-216658 | |
| AMPK | AMOTL1 | Ser793 | SSLRPARsVPSIAAA | phosphorylation up-regulates quantity by stabilization | 25373897 | SIGNOR-263105 |
| AMPK | PDHA1 | Ser314 | IQEVRSKsDPIMLLK | phosphorylation up-regulates activity | 33022274 | SIGNOR-276836 |
| AMPK | EEF2K | Ser398 | DSLPSSPsSATPHSQ | phosphorylation up-regulates | 22669845 | SIGNOR-216503 |
| AMPK | RAF1 | Ser621 | PKINRSAsEPSLHRA | phosphorylation up-regulates | 9091312 | SIGNOR-216616 |
| AMPK | ULK1 | Ser317 | SHLASPPsLGEMQQL | phosphorylation up-regulates | 19584320 | SIGNOR-216491 |
| AMPK | FOXO3 | Ser399 | DNITLPPsQPSPTGG | phosphorylation up-regulates activity | 17711846 | SIGNOR-249668 |
| AMPK | FOXO3 | Ser413 | GLMQRSSsFPYTTKG | phosphorylation up-regulates activity | 22848740 | SIGNOR-255756 |
| AMPK | RRN3 | Ser635 | DTHFRSPsSSVGSPP | phosphorylation down-regulates | 19815529 | SIGNOR-216592 |
| AMPK | FOXO3 | Ser588 | QTLSDSLsGSSLYST | phosphorylation up-regulates activity | 17711846 | SIGNOR-249685 |
| AMPK | EPM2A | Ser25 | PELLVVGsRPELGRW | phosphorylation up-regulates activity | 21728993 | SIGNOR-276338 |
| AMPK | MCU | Ser57 | TVHQRIAsWQNLGAV | phosphorylation up-regulates activity | 30858581 | SIGNOR-275548 |
| AMPK | ULK1 | Ser556 | GLGCRLHsAPNLSDL | phosphorylation up-regulates | 21205641 | SIGNOR-216457 |
| AMPK | PPARGC1A | Ser539 | SLFNVSPsCSSFNSP | phosphorylation up-regulates activity | 17609368 | SIGNOR-228646 |
| AMPK | PFKFB2 | Ser466 | PVRMRRNsFTPLSSS | phosphorylation up-regulates activity | 11069105 | SIGNOR-216623 |
| AMPK | FOXO | Thr179 | SSPDKRLtLSQIYEW | phosphorylation up-regulates activity | 17711846 | SIGNOR-252885 |
| AMPK | ATG9A | Ser761 | QSIPRSAsYPCAAPR | phosphorylation up-regulates activity | 25266655 | SIGNOR-266365 |
| AMPK | ULK1/Atg13/Fip200 | – | phosphorylation up-regulates activity | 23863160 | SIGNOR-209913 | |
| AMPK | FOXO | Ser555 | RALSNSVsNMGLSES | phosphorylation up-regulates activity | 17711846 | SIGNOR-252882 |
| AMPK | PDHA1 | Ser295 | RYHGHSMsDPGVSYR | phosphorylation up-regulates activity | 33022274 | SIGNOR-277895 |
| AMPK | KCNA5 | Ser559 | VQRKVSGsRGSFCKA | phosphorylation down-regulates activity | 30279167 | SIGNOR-273736 |
| AMPK | VASP | Ser322 | TTLPRMKsSSSVTTS | phosphorylation down-regulates | 21945940 | SIGNOR-216568 |
| AMPK | NEDD4L | Ser795 | VDLKPNGsEIMVTNE | phosphorylation up-regulates activity | 21501591 | SIGNOR-276324 |
| AMPK | SLC9A3 | Ser555 | AEGERRGsLAFIRSP | phosphorylation down-regulates activity | 38047302 | SIGNOR-277849 |
| AMPK | PFKFB3 | Ser461 | NPLMRRNsVTPLASP | phosphorylation up-regulates | 12065600 | SIGNOR-216639 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | phosphorylation up-regulates → | CRY1 PSer71 | phosphorylation down-regulates ⊣ | CRY1 | 19833968 | SIGNOR-268046 |
| AMPK | phosphorylation up-regulates → | RAF1 PSer259 | phosphorylation down-regulates ⊣ | RAF1 | 11971957 | SIGNOR-216523 |
| AMPK | phosphorylation up-regulates → | NEDD4L PSer795 | phosphorylation up-regulates → | NEDD4L | 21501591 | SIGNOR-277858 |
| AMPK | phosphorylation up-regulates → | DNMT1 PSer714 | phosphorylation down-regulates ⊣ | DNMT1 | 28143904 | SIGNOR-264788 |
| AMPK | phosphorylation up-regulates → | HNF4A PSer303 | phosphorylation down-regulates ⊣ | HNF4A | 12740371 | SIGNOR-216511 |
| AMPK | phosphorylation up-regulates → | HDAC5 PSer259 | phosphorylation down-regulates ⊣ | HDAC5 | 21892142 | SIGNOR-216596 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer626 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249688 |
| AMPK | phosphorylation up-regulates → | MAPT PSer396 | phosphorylation down-regulates ⊣ | MAPT | 21204788 | SIGNOR-273930 |
| AMPK | phosphorylation up-regulates → | RBBP7 PSer314 | phosphorylation up-regulates → | RBBP7 | 28143904 | SIGNOR-264789 |
| AMPK | phosphorylation up-regulates → | CTH PSer346 | phosphorylation up-regulates → | CTH | 37922764 | SIGNOR-277808 |
| AMPK | phosphorylation up-regulates → | HDAC7 PSer155 | phosphorylation down-regulates ⊣ | HDAC7 | 21892142 | SIGNOR-216554 |
| AMPK | phosphorylation up-regulates → | ULK1 PSer638 | phosphorylation up-regulates → | ULK1 | 19584320 | SIGNOR-216499 |
| AMPK | phosphorylation up-regulates → | CRTC2 PSer171 | phosphorylation down-regulates ⊣ | CRTC2 | 20577053 | SIGNOR-216576 |
| AMPK | phosphorylation up-regulates → | ULK1 PSer638 | phosphorylation up-regulates → | ULK1 | 21205641 | SIGNOR-216461 |
| AMPK | phosphorylation up-regulates → | FOXO3 PThr179 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-274094 |
| AMPK | phosphorylation up-regulates → | TXNIP PSer308 | phosphorylation down-regulates ⊣ | TXNIP | 23453806 | SIGNOR-276489 |
| AMPK | phosphorylation up-regulates → | ULK1 PSer317 | phosphorylation up-regulates → | ULK1 | 21205641 | SIGNOR-216453 |
| AMPK | phosphorylation up-regulates → | CRY1 PSer71 | phosphorylation down-regulates ⊣ | CRY1 | 21892142 | SIGNOR-216546 |
| AMPK | phosphorylation up-regulates → | GYS1 PSer8 | phosphorylation down-regulates ⊣ | GYS1 | 22233421 | SIGNOR-263102 |
| AMPK | phosphorylation up-regulates → | HNF4A PSer303 | phosphorylation down-regulates ⊣ | HNF4A | 12740371 | SIGNOR-263106 |
| AMPK | phosphorylation up-regulates → | PPP1R12C PSer452 | phosphorylation down-regulates ⊣ | PPP1R12C | 22137581 | SIGNOR-216600 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer555 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249682 |
| AMPK | phosphorylation up-regulates → | CCNY PSer326 | phosphorylation up-regulates → | CCNY | 32723157 | SIGNOR-273001 |
| AMPK | phosphorylation up-regulates → | NR2C2 PSer351 | phosphorylation down-regulates ⊣ | NR2C2 | 21478464 | SIGNOR-216537 |
| AMPK | phosphorylation up-regulates → | GLI1 PSer408 | phosphorylation down-regulates ⊣ | GLI1 | 26190112 | SIGNOR-253541 |
| AMPK | phosphorylation up-regulates → | PFKFB2 PSer466 | phosphorylation up-regulates → | PFKFB2 | 20640476 | SIGNOR-209947 |
| AMPK | phosphorylation up-regulates → | RPTOR PSer792 | phosphorylation down-regulates ⊣ | RPTOR | 18439900 | SIGNOR-263044 |
| AMPK | phosphorylation up-regulates → | HAT1 PSer190 | phosphorylation up-regulates → | HAT1 | 28143904 | SIGNOR-264787 |
| AMPK | phosphorylation up-regulates → | VASP PThr278 | phosphorylation down-regulates ⊣ | VASP | 17082196 | SIGNOR-216515 |
| AMPK | phosphorylation up-regulates → | PPP1R3C PSer33 | phosphorylation down-regulates ⊣ | PPP1R3C | 19171932 | SIGNOR-276237 |
| AMPK | phosphorylation up-regulates → | FOXO PSer626 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252884 |
| AMPK | phosphorylation up-regulates → | PPP1R3C PSer33 | phosphorylation down-regulates ⊣ | PPP1R3C | 19171932 | SIGNOR-273739 |
| AMPK | phosphorylation up-regulates → | CDC27 PSer379 | phosphorylation down-regulates ⊣ | CDC27 | 22137581 | SIGNOR-216434 |
| AMPK | phosphorylation up-regulates → | CRY1 PSer280 | phosphorylation down-regulates ⊣ | CRY1 | 19833968 | SIGNOR-268047 |
| AMPK | phosphorylation up-regulates → | SCN5A PThr101 | phosphorylation up-regulates → | SCN5A | 33410863 | SIGNOR-275769 |
| AMPK | phosphorylation up-regulates → | LIPE PSer855 | phosphorylation down-regulates ⊣ | LIPE | 9636039 | SIGNOR-216507 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer555 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-274093 |
| AMPK | phosphorylation up-regulates → | SLC12A2 PSer77 | phosphorylation down-regulates ⊣ | SLC12A2 | 24702155 | SIGNOR-276630 |
| AMPK | phosphorylation up-regulates → | EPM2A PSer25 | phosphorylation up-regulates → | EPM2A | 21728993 | SIGNOR-277830 |
| AMPK | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 15866171 | SIGNOR-216475 |
| AMPK | phosphorylation up-regulates → | FH PSer75 | phosphorylation up-regulates → | FH | 28628081 | SIGNOR-266313 |
| AMPK | phosphorylation up-regulates → | HDAC5 PSer498 | phosphorylation down-regulates ⊣ | HDAC5 | 21892142 | SIGNOR-216550 |
| AMPK | phosphorylation up-regulates → | CFTR PSer737 | phosphorylation down-regulates ⊣ | CFTR | 19095655 | SIGNOR-250350 |
| AMPK | phosphorylation up-regulates → | MAPT PSer262 | phosphorylation down-regulates ⊣ | MAPT | 21204788 | SIGNOR-273928 |
| AMPK | phosphorylation up-regulates → | YBX2 PThr115 | phosphorylation up-regulates → | YBX2 | 37860762 | SIGNOR-277868 |
| AMPK | phosphorylation up-regulates → | MAPT PThr231 | phosphorylation down-regulates ⊣ | MAPT | 21204788 | SIGNOR-273927 |
| AMPK | phosphorylation up-regulates → | NOS3 PSer1177 | phosphorylation up-regulates → | NOS3 | 18303014 | SIGNOR-216627 |
| AMPK | phosphorylation up-regulates → | PPARGC1A PSer539 | phosphorylation up-regulates → | PPARGC1A | 17609368 | SIGNOR-216647 |
| AMPK | phosphorylation up-regulates → | CHKA PSer279 | phosphorylation up-regulates → | CHKA | 34929314 | SIGNOR-267647 |
| AMPK | phosphorylation up-regulates → | ARMC10 PSer45 | phosphorylation up-regulates → | ARMC10 | 30631047 | SIGNOR-266413 |
| AMPK | phosphorylation up-regulates → | KLC2 PSer582 | phosphorylation up-regulates → | KLC2 | 21725060 | SIGNOR-216468 |
| AMPK | phosphorylation up-regulates → | PRPS1 PSer180 | phosphorylation down-regulates ⊣ | PRPS1 | 29074724 | SIGNOR-265730 |
| AMPK | phosphorylation up-regulates → | MLXIPL PSer556 | phosphorylation down-regulates ⊣ | MLXIPL | 11724780 | SIGNOR-216526 |
| AMPK | phosphorylation up-regulates → | FOXO PSer399 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252880 |
| AMPK | phosphorylation up-regulates → | GAPDH PSer122 | phosphorylation up-regulates → | GAPDH | 26626483 | SIGNOR-267578 |
| AMPK | phosphorylation up-regulates → | NOS3 PThr495 | phosphorylation down-regulates ⊣ | NOS3 | 24379783 | SIGNOR-251618 |
| AMPK | phosphorylation up-regulates → | KPNA2 PSer105 | phosphorylation up-regulates → | KPNA2 | 15342649 | SIGNOR-216449 |
| AMPK | phosphorylation up-regulates → | PIKFYVE PSer307 | phosphorylation up-regulates → | PIKFYVE | 23905686 | SIGNOR-263031 |
| AMPK | phosphorylation up-regulates → | NEDD4L PSer795 | phosphorylation up-regulates → | NEDD4L | 21501591 | SIGNOR-276326 |
| AMPK | phosphorylation up-regulates → | RB1 PSer811 | phosphorylation down-regulates ⊣ | RB1 | 19217427 | SIGNOR-216635 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer413 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-274098 |
| AMPK | phosphorylation up-regulates → | PRPS2 PSer180 | phosphorylation down-regulates ⊣ | PRPS2 | 29074724 | SIGNOR-265732 |
| AMPK | phosphorylation up-regulates → | ACACA PSer80 | phosphorylation down-regulates ⊣ | ACACA | 12015362 | SIGNOR-216655 |
| AMPK | phosphorylation up-regulates → | ZNF692 PSer470 | phosphorylation down-regulates ⊣ | ZNF692 | 17097062 | SIGNOR-216519 |
| AMPK | phosphorylation up-regulates → | GLI1 PThr1074 | phosphorylation down-regulates ⊣ | GLI1 | 26190112 | SIGNOR-253543 |
| AMPK | phosphorylation up-regulates → | SLC9A3 PSer563 | phosphorylation down-regulates ⊣ | SLC9A3 | 38047302 | SIGNOR-277848 |
| AMPK | phosphorylation up-regulates → | YAP1 PSer94 | phosphorylation down-regulates ⊣ | YAP1 | 25751140 | SIGNOR-277638 |
| AMPK | phosphorylation up-regulates → | MFF PSer155 | phosphorylation up-regulates → | MFF | 26816379 | SIGNOR-245948 |
| AMPK | phosphorylation up-regulates → | PDHA1 PSer314 | phosphorylation up-regulates → | PDHA1 | 33022274 | SIGNOR-277894 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer413 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249678 |
| AMPK | phosphorylation up-regulates → | MFF PSer172 | phosphorylation up-regulates → | MFF | 26816379 | SIGNOR-249655 |
| AMPK | phosphorylation up-regulates → | ACSS2 PSer659 | phosphorylation up-regulates → | ACSS2 | 28820290 | SIGNOR-271823 |
| AMPK | phosphorylation up-regulates → | MAPT PSer352 | phosphorylation down-regulates ⊣ | MAPT | 21204788 | SIGNOR-273929 |
| AMPK | phosphorylation up-regulates → | CTBP1 PSer158 | phosphorylation down-regulates ⊣ | CTBP1 | 23291169 | SIGNOR-216604 |
| AMPK | phosphorylation up-regulates → | MAPT PSer214 | phosphorylation down-regulates ⊣ | MAPT | 21204788 | SIGNOR-273926 |
| AMPK | phosphorylation up-regulates → | KCNA5 PSer592 | phosphorylation down-regulates ⊣ | KCNA5 | 30279167 | SIGNOR-273735 |
| AMPK | phosphorylation up-regulates → | PAQR3 PThr32 | phosphorylation up-regulates → | PAQR3 | 26834238 | SIGNOR-273737 |
| AMPK | phosphorylation up-regulates → | PLD1 PSer505 | phosphorylation up-regulates → | PLD1 | 20231899 | SIGNOR-216643 |
| AMPK | phosphorylation up-regulates → | HIPK2 PSer121 | phosphorylation down-regulates ⊣ | HIPK2 | 23871434 | SIGNOR-275483 |
| AMPK | phosphorylation up-regulates → | MAPT PSer420 | phosphorylation down-regulates ⊣ | MAPT | 21204788 | SIGNOR-273931 |
| AMPK | phosphorylation up-regulates → | GBF1 PThr1337 | phosphorylation down-regulates ⊣ | GBF1 | 18063581 | SIGNOR-216588 |
| AMPK | phosphorylation up-regulates → | PPARGC1A PThr178 | phosphorylation up-regulates → | PPARGC1A | 20640476 | SIGNOR-209936 |
| AMPK | phosphorylation up-regulates → | BAIAP2 PSer366 | phosphorylation down-regulates ⊣ | BAIAP2 | 22137581 | SIGNOR-216608 |
| AMPK | phosphorylation up-regulates → | GYS2 PSer8 | phosphorylation down-regulates ⊣ | GYS2 | 22233421 | SIGNOR-263101 |
| AMPK | phosphorylation up-regulates → | HDAC7 PSer358 | phosphorylation down-regulates ⊣ | HDAC7 | 21892142 | SIGNOR-216558 |
| AMPK | phosphorylation up-regulates → | FOXO3 PThr179 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-238813 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer626 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-274097 |
| AMPK | phosphorylation up-regulates → | SREBF1 PSer396 | phosphorylation down-regulates ⊣ | SREBF1 | 21459323 | SIGNOR-216533 |
| AMPK | phosphorylation up-regulates → | CTH PThr355 | phosphorylation up-regulates → | CTH | 37922764 | SIGNOR-277793 |
| AMPK | phosphorylation up-regulates → | CTH PThr355 | phosphorylation up-regulates → | CTH | 37922764 | SIGNOR-277807 |
| AMPK | phosphorylation up-regulates → | FOXO PSer413 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252881 |
| AMPK | phosphorylation up-regulates → | CFTR PSer768 | phosphorylation down-regulates ⊣ | CFTR | 19095655 | SIGNOR-72708 |
| AMPK | phosphorylation up-regulates → | CTH PSer346 | phosphorylation up-regulates → | CTH | 37922764 | SIGNOR-277794 |
| AMPK | phosphorylation up-regulates → | SIRT7 PThr153 | phosphorylation down-regulates ⊣ | SIRT7 | 27511885 | SIGNOR-275865 |
| AMPK | phosphorylation up-regulates → | TET2 PSer99 | phosphorylation up-regulates → | TET2 | 30022161 | SIGNOR-256135 |
| AMPK | phosphorylation up-regulates → | TBC1D1 PSer237 | phosphorylation down-regulates ⊣ | TBC1D1 | 17995453 | SIGNOR-216631 |
| AMPK | phosphorylation up-regulates → | HIPK2 PThr119 | phosphorylation down-regulates ⊣ | HIPK2 | 23871434 | SIGNOR-275482 |
| AMPK | phosphorylation up-regulates → | CRTC2 PSer170 | phosphorylation down-regulates ⊣ | CRTC2 | 21892142 | SIGNOR-216541 |
| AMPK | phosphorylation up-regulates → | HIPK2 PThr1116 | phosphorylation down-regulates ⊣ | HIPK2 | 23871434 | SIGNOR-275484 |
| AMPK | phosphorylation up-regulates → | ARMC10 PSer45 | phosphorylation up-regulates → | ARMC10 | 30631047 | SIGNOR-277806 |
| AMPK | phosphorylation up-regulates → | SLC12A1 PSer122 | phosphorylation up-regulates → | SLC12A1 | 17341212 | SIGNOR-263103 |
| AMPK | phosphorylation up-regulates → | ALDH2 PThr356 | phosphorylation up-regulates → | ALDH2 | 30375985 | SIGNOR-271862 |
| AMPK | phosphorylation up-regulates → | CSNK1E PSer389 | phosphorylation up-regulates → | CSNK1E | 17525164 | SIGNOR-276064 |
| AMPK | phosphorylation up-regulates → | PDHA1 PSer295 | phosphorylation up-regulates → | PDHA1 | 33022274 | SIGNOR-276835 |
| AMPK | phosphorylation up-regulates → | GLI1 PSer102 | phosphorylation down-regulates ⊣ | GLI1 | 26190112 | SIGNOR-253542 |
| AMPK | phosphorylation up-regulates → | FOXO PSer588 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252883 |
| AMPK | phosphorylation up-regulates → | MTOR PSer1261 | phosphorylation up-regulates → | MTOR | 31186373 | SIGNOR-262535 |
| AMPK | phosphorylation up-regulates → | PPARGC1A PThr178 | phosphorylation up-regulates → | PPARGC1A | 17609368 | SIGNOR-216651 |
| AMPK | phosphorylation up-regulates → | PRKAA1 PSer486 | phosphorylation down-regulates ⊣ | PRKAA1 | 17023420 | SIGNOR-256113 |
| AMPK | phosphorylation up-regulates → | ARMC10 PSer45 | phosphorylation up-regulates → | ARMC10 | 30631047 | SIGNOR-277792 |
| AMPK | phosphorylation up-regulates → | PPARGC1A PThr178 | phosphorylation up-regulates → | PPARGC1A | 17609368 | SIGNOR-228642 |
| AMPK | phosphorylation up-regulates → | BAIAP2 PSer366 | phosphorylation down-regulates ⊣ | BAIAP2 | 19933840 | SIGNOR-216572 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer588 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-274096 |
| AMPK | phosphorylation up-regulates → | GLI1 PSer408 | phosphorylation down-regulates ⊣ | GLI1 | 26843621 | SIGNOR-253540 |
| AMPK | phosphorylation up-regulates → | PPARGC1A PSer539 | phosphorylation up-regulates → | PPARGC1A | 20640476 | SIGNOR-209940 |
| AMPK | phosphorylation up-regulates → | PFKFB2 PSer466 | phosphorylation up-regulates → | PFKFB2 | 11069105 | SIGNOR-260011 |
| AMPK | phosphorylation up-regulates → | NOS3 PSer1177 | phosphorylation up-regulates → | NOS3 | 11729179 | SIGNOR-216445 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer399 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-274095 |
| AMPK | phosphorylation up-regulates → | PAK2 PSer20 | phosphorylation down-regulates ⊣ | PAK2 | 22137581 | SIGNOR-216612 |
| AMPK | phosphorylation up-regulates → | TSC2 PSer1387 | phosphorylation up-regulates → | TSC2 | 16959574 | SIGNOR-216438 |
| AMPK | phosphorylation up-regulates → | RPTOR PSer722 | phosphorylation down-regulates ⊣ | RPTOR | 18439900 | SIGNOR-263046 |
| AMPK | phosphorylation up-regulates → | ACACA PSer80 | phosphorylation down-regulates ⊣ | ACACA | 29899443 | SIGNOR-267475 |
| AMPK | phosphorylation up-regulates → | ULK1 PSer556 | phosphorylation up-regulates → | ULK1 | 19584320 | SIGNOR-216495 |
| AMPK | phosphorylation up-regulates → | AMOTL1 PSer793 | phosphorylation up-regulates → | AMOTL1 | 25373897 | SIGNOR-263105 |
| AMPK | phosphorylation up-regulates → | PDHA1 PSer314 | phosphorylation up-regulates → | PDHA1 | 33022274 | SIGNOR-276836 |
| AMPK | phosphorylation up-regulates → | EEF2K PSer398 | phosphorylation up-regulates → | EEF2K | 22669845 | SIGNOR-216503 |
| AMPK | phosphorylation up-regulates → | RAF1 PSer621 | phosphorylation up-regulates → | RAF1 | 9091312 | SIGNOR-216616 |
| AMPK | phosphorylation up-regulates → | ULK1 PSer317 | phosphorylation up-regulates → | ULK1 | 19584320 | SIGNOR-216491 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer399 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249668 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer413 | phosphorylation up-regulates → | FOXO3 | 22848740 | SIGNOR-255756 |
| AMPK | phosphorylation up-regulates → | RRN3 PSer635 | phosphorylation down-regulates ⊣ | RRN3 | 19815529 | SIGNOR-216592 |
| AMPK | phosphorylation up-regulates → | FOXO3 PSer588 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249685 |
| AMPK | phosphorylation up-regulates → | EPM2A PSer25 | phosphorylation up-regulates → | EPM2A | 21728993 | SIGNOR-276338 |
| AMPK | phosphorylation up-regulates → | MCU PSer57 | phosphorylation up-regulates → | MCU | 30858581 | SIGNOR-275548 |
| AMPK | phosphorylation up-regulates → | ULK1 PSer556 | phosphorylation up-regulates → | ULK1 | 21205641 | SIGNOR-216457 |
| AMPK | phosphorylation up-regulates → | PPARGC1A PSer539 | phosphorylation up-regulates → | PPARGC1A | 17609368 | SIGNOR-228646 |
| AMPK | phosphorylation up-regulates → | PFKFB2 PSer466 | phosphorylation up-regulates → | PFKFB2 | 11069105 | SIGNOR-216623 |
| AMPK | phosphorylation up-regulates → | FOXO PThr179 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252885 |
| AMPK | phosphorylation up-regulates → | ATG9A PSer761 | phosphorylation up-regulates → | ATG9A | 25266655 | SIGNOR-266365 |
| AMPK | phosphorylation up-regulates → | FOXO PSer555 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252882 |
| AMPK | phosphorylation up-regulates → | PDHA1 PSer295 | phosphorylation up-regulates → | PDHA1 | 33022274 | SIGNOR-277895 |
| AMPK | phosphorylation up-regulates → | KCNA5 PSer559 | phosphorylation down-regulates ⊣ | KCNA5 | 30279167 | SIGNOR-273736 |
| AMPK | phosphorylation up-regulates → | VASP PSer322 | phosphorylation down-regulates ⊣ | VASP | 21945940 | SIGNOR-216568 |
| AMPK | phosphorylation up-regulates → | NEDD4L PSer795 | phosphorylation up-regulates → | NEDD4L | 21501591 | SIGNOR-276324 |
| AMPK | phosphorylation up-regulates → | SLC9A3 PSer555 | phosphorylation down-regulates ⊣ | SLC9A3 | 38047302 | SIGNOR-277849 |
| AMPK | phosphorylation up-regulates → | PFKFB3 PSer461 | phosphorylation up-regulates → | PFKFB3 | 12065600 | SIGNOR-216639 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AMPK | phosphorylation down-regulates quantity by destabilization | CRY1 | SIGNOR-268046 |
| AMPK | phosphorylation down-regulates | RAF1 | SIGNOR-216523 |
| AMPK | phosphorylation → up-regulates | INSR | SIGNOR-216619 |
| AMPK | phosphorylation → down-regulates activity | mTORC1 | SIGNOR-216422 |
| AMPK | phosphorylation → up-regulates activity | NEDD4L | SIGNOR-277858 |
| AMPK | phosphorylation → down-regulates activity | DNMT1 | SIGNOR-264788 |
| AMPK | phosphorylation down-regulates | HNF4A | SIGNOR-216511 |
| AMPK | phosphorylation down-regulates | HDAC5 | SIGNOR-216596 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249688 |
| AMPK | phosphorylation → up-regulates activity | EPM2A | SIGNOR-271730 |
| AMPK | phosphorylation down-regulates | CRTC1 | SIGNOR-216529 |
| AMPK | phosphorylation → down-regulates activity | MAPT | SIGNOR-273930 |
| AMPK | phosphorylation → up-regulates activity | RBBP7 | SIGNOR-264789 |
| AMPK | phosphorylation → up-regulates activity | CTH | SIGNOR-277808 |
| AMPK | phosphorylation down-regulates | HDAC7 | SIGNOR-216554 |
| AMPK | phosphorylation → up-regulates | TSC1 | SIGNOR-216441 |
| AMPK | phosphorylation → up-regulates | ULK1 | SIGNOR-216499 |
| AMPK | phosphorylation down-regulates | CRTC2 | SIGNOR-216576 |
| AMPK | phosphorylation → up-regulates | ULK1 | SIGNOR-216461 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-274094 |
| AMPK | phosphorylation down-regulates quantity by destabilization | TXNIP | SIGNOR-276489 |
| AMPK | phosphorylation → up-regulates activity | TET2 | SIGNOR-260097 |
| AMPK | phosphorylation → up-regulates | ULK1 | SIGNOR-216453 |
| AMPK | phosphorylation down-regulates | CRY1 | SIGNOR-216546 |
| AMPK | phosphorylation → down-regulates activity | GYS1 | SIGNOR-263102 |
| AMPK | phosphorylation → down-regulates activity | HNF4A | SIGNOR-263106 |
| AMPK | phosphorylation down-regulates | PPP1R12C | SIGNOR-216600 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249682 |
| AMPK | phosphorylation → up-regulates activity | CCNY | SIGNOR-273001 |
| AMPK | phosphorylation down-regulates | NR2C2 | SIGNOR-216537 |
| AMPK | phosphorylation down-regulates quantity by destabilization | GLI1 | SIGNOR-253541 |
| AMPK | phosphorylation → up-regulates activity | PFKFB2 | SIGNOR-209947 |
| AMPK | phosphorylation down-regulates | RPTOR | SIGNOR-263044 |
| AMPK | phosphorylation → up-regulates activity | TSC | SIGNOR-217749 |
| AMPK | phosphorylation → up-regulates activity | HAT1 | SIGNOR-264787 |
| AMPK | phosphorylation down-regulates | VASP | SIGNOR-216515 |
| AMPK | phosphorylation down-regulates quantity by destabilization | PPP1R3C | SIGNOR-276237 |
| AMPK | phosphorylation → up-regulates activity | FOXO | SIGNOR-252884 |
| AMPK | phosphorylation down-regulates quantity by destabilization | PPP1R3C | SIGNOR-273739 |
| AMPK | phosphorylation → unknown | CDC27 | SIGNOR-216434 |
| AMPK | phosphorylation down-regulates quantity by destabilization | CRY1 | SIGNOR-268047 |
| AMPK | phosphorylation → up-regulates activity | SCN5A | SIGNOR-275769 |
| AMPK | phosphorylation down-regulates | LIPE | SIGNOR-216507 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-274093 |
| AMPK | phosphorylation → down-regulates activity | SLC12A2 | SIGNOR-276630 |
| AMPK | phosphorylation → up-regulates activity | EPM2A | SIGNOR-277830 |
| AMPK | phosphorylation → up-regulates activity | WDR45 | SIGNOR-268480 |
| AMPK | phosphorylation → up-regulates | TP53 | SIGNOR-216475 |
| AMPK | phosphorylation → up-regulates activity | AMPK | SIGNOR-216411 |
| AMPK | phosphorylation → up-regulates activity | FH | SIGNOR-266313 |
| AMPK | phosphorylation down-regulates | HDAC5 | SIGNOR-216550 |
| AMPK | phosphorylation → down-regulates activity | CFTR | SIGNOR-250350 |
| AMPK | phosphorylation → down-regulates activity | MAPT | SIGNOR-273928 |
| AMPK | phosphorylation → down-regulates activity | mTORC1 | SIGNOR-209862 |
| AMPK | phosphorylation → up-regulates quantity by stabilization | YBX2 | SIGNOR-277868 |
| AMPK | phosphorylation → up-regulates | FOXO | SIGNOR-252886 |
| AMPK | phosphorylation → down-regulates activity | MAPT | SIGNOR-273927 |
| AMPK | phosphorylation down-regulates | MLXIPL | SIGNOR-216561 |
| AMPK | phosphorylation → up-regulates | NOS3 | SIGNOR-216627 |
| AMPK | phosphorylation → up-regulates | PPARGC1A | SIGNOR-216647 |
| AMPK | phosphorylation → up-regulates activity | CHKA | SIGNOR-267647 |
| AMPK | phosphorylation → up-regulates activity | ARMC10 | SIGNOR-266413 |
| AMPK | phosphorylation → up-regulates | KLC2 | SIGNOR-216468 |
| AMPK | phosphorylation → down-regulates activity | PRPS1 | SIGNOR-265730 |
| AMPK | phosphorylation down-regulates | MLXIPL | SIGNOR-216526 |
| AMPK | phosphorylation → up-regulates activity | FOXO | SIGNOR-252880 |
| AMPK | phosphorylation → down-regulates activity | mTORC1 | SIGNOR-216418 |
| AMPK | phosphorylation → up-regulates activity | GAPDH | SIGNOR-267578 |
| AMPK | phosphorylation → down-regulates activity | NOS3 | SIGNOR-251618 |
| AMPK | phosphorylation → up-regulates | KPNA2 | SIGNOR-216449 |
| AMPK | phosphorylation → up-regulates activity | PIKFYVE | SIGNOR-263031 |
| AMPK | phosphorylation → up-regulates activity | NEDD4L | SIGNOR-276326 |
| AMPK | phosphorylation → unknown | RB1 | SIGNOR-216635 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-274098 |
| AMPK | phosphorylation → down-regulates activity | PRPS2 | SIGNOR-265732 |
| AMPK | phosphorylation down-regulates | ACACA | SIGNOR-216655 |
| AMPK | phosphorylation down-regulates | ZNF692 | SIGNOR-216519 |
| AMPK | phosphorylation down-regulates quantity by destabilization | GLI1 | SIGNOR-253543 |
| AMPK | phosphorylation → down-regulates activity | SLC9A3 | SIGNOR-277848 |
| AMPK | phosphorylation → down-regulates activity | YAP1 | SIGNOR-277638 |
| AMPK | phosphorylation → up-regulates activity | MFF | SIGNOR-245948 |
| AMPK | phosphorylation → up-regulates activity | PDHA1 | SIGNOR-277894 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249678 |
| AMPK | phosphorylation → up-regulates activity | MFF | SIGNOR-249655 |
| AMPK | phosphorylation → up-regulates | Gbeta | SIGNOR-216471 |
| AMPK | phosphorylation down-regulates | SREBF1 | SIGNOR-216564 |
| AMPK | phosphorylation → up-regulates activity | ACSS2 | SIGNOR-271823 |
| AMPK | phosphorylation → down-regulates activity | MAPT | SIGNOR-273929 |
| AMPK | phosphorylation down-regulates | CTBP1 | SIGNOR-216604 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-216481 |
| AMPK | phosphorylation → up-regulates activity | FOXO | SIGNOR-252889 |
| AMPK | phosphorylation → down-regulates activity | MAPT | SIGNOR-273926 |
| AMPK | phosphorylation → down-regulates activity | KCNA5 | SIGNOR-273735 |
| AMPK | phosphorylation → up-regulates activity | PAQR3 | SIGNOR-273737 |
| AMPK | phosphorylation → up-regulates | PLD1 | SIGNOR-216643 |
| AMPK | phosphorylation → down-regulates activity | HIPK2 | SIGNOR-275483 |
| AMPK | phosphorylation → down-regulates activity | MAPT | SIGNOR-273931 |
| AMPK | phosphorylation → unknown | AMPK | SIGNOR-216415 |
| AMPK | phosphorylation down-regulates | GBF1 | SIGNOR-216588 |
| AMPK | phosphorylation → up-regulates activity | PPARGC1A | SIGNOR-209936 |
| AMPK | phosphorylation down-regulates | BAIAP2 | SIGNOR-216608 |
| AMPK | phosphorylation → down-regulates activity | GYS2 | SIGNOR-263101 |
| AMPK | phosphorylation down-regulates | HDAC7 | SIGNOR-216558 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-238813 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-274097 |
| AMPK | phosphorylation down-regulates | SREBF1 | SIGNOR-216533 |
| AMPK | phosphorylation → up-regulates activity | CTH | SIGNOR-277793 |
| AMPK | phosphorylation → up-regulates activity | CTH | SIGNOR-277807 |
| AMPK | phosphorylation → down-regulates activity | mTORC1 | SIGNOR-216430 |
| AMPK | phosphorylation → up-regulates activity | FOXO | SIGNOR-252881 |
| AMPK | phosphorylation → down-regulates activity | CFTR | SIGNOR-72708 |
| AMPK | phosphorylation → up-regulates activity | CTH | SIGNOR-277794 |
| AMPK | phosphorylation down-regulates quantity by destabilization | SIRT7 | SIGNOR-275865 |
| AMPK | phosphorylation → up-regulates quantity by stabilization | TET2 | SIGNOR-256135 |
| AMPK | phosphorylation down-regulates | TBC1D1 | SIGNOR-216631 |
| AMPK | phosphorylation → up-regulates | ULK1 | SIGNOR-216464 |
| AMPK | phosphorylation → down-regulates activity | HIPK2 | SIGNOR-275482 |
| AMPK | phosphorylation down-regulates | CRTC2 | SIGNOR-216541 |
| AMPK | phosphorylation → down-regulates activity | HIPK2 | SIGNOR-275484 |
| AMPK | phosphorylation → up-regulates activity | ARMC10 | SIGNOR-277806 |
| AMPK | phosphorylation → up-regulates activity | SLC12A1 | SIGNOR-263103 |
| AMPK | phosphorylation → up-regulates activity | ALDH2 | SIGNOR-271862 |
| AMPK | phosphorylation → up-regulates activity | CSNK1E | SIGNOR-276064 |
| AMPK | phosphorylation → up-regulates | FOXO1 | SIGNOR-216478 |
| AMPK | phosphorylation → up-regulates activity | PDHA1 | SIGNOR-276835 |
| AMPK | phosphorylation down-regulates quantity by destabilization | GLI1 | SIGNOR-253542 |
| AMPK | phosphorylation → up-regulates activity | FOXO | SIGNOR-252883 |
| AMPK | phosphorylation → up-regulates activity | MTOR | SIGNOR-262535 |
| AMPK | phosphorylation → up-regulates | PPARGC1A | SIGNOR-216651 |
| AMPK | phosphorylation → down-regulates activity | PRKAA1 | SIGNOR-256113 |
| AMPK | phosphorylation → up-regulates activity | ARMC10 | SIGNOR-277792 |
| AMPK | phosphorylation → up-regulates activity | PPARGC1A | SIGNOR-228642 |
| AMPK | phosphorylation down-regulates | BAIAP2 | SIGNOR-216572 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-274096 |
| AMPK | phosphorylation down-regulates quantity by destabilization | GLI1 | SIGNOR-253540 |
| AMPK | phosphorylation → up-regulates activity | PPARGC1A | SIGNOR-209940 |
| AMPK | phosphorylation → up-regulates activity | PFKFB2 | SIGNOR-260011 |
| AMPK | phosphorylation → up-regulates | NOS3 | SIGNOR-216445 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-274095 |
| AMPK | phosphorylation → unknown | PAK2 | SIGNOR-216612 |
| AMPK | phosphorylation → up-regulates | TSC2 | SIGNOR-216438 |
| AMPK | phosphorylation down-regulates | RPTOR | SIGNOR-263046 |
| AMPK | phosphorylation → up-regulates | TSC1 | SIGNOR-216487 |
| AMPK | phosphorylation → up-regulates | FOXO4 | SIGNOR-216484 |
| AMPK | phosphorylation → down-regulates activity | ACACA | SIGNOR-267475 |
| AMPK | phosphorylation → up-regulates | ULK1 | SIGNOR-216495 |
| AMPK | phosphorylation down-regulates | HDAC4 | SIGNOR-216658 |
| AMPK | phosphorylation → up-regulates quantity by stabilization | AMOTL1 | SIGNOR-263105 |
| AMPK | phosphorylation → up-regulates activity | PDHA1 | SIGNOR-276836 |
| AMPK | phosphorylation → up-regulates | EEF2K | SIGNOR-216503 |
| AMPK | phosphorylation → up-regulates | RAF1 | SIGNOR-216616 |
| AMPK | phosphorylation → up-regulates | ULK1 | SIGNOR-216491 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249668 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-255756 |
| AMPK | phosphorylation down-regulates | RRN3 | SIGNOR-216592 |
| AMPK | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249685 |
| AMPK | phosphorylation → up-regulates activity | EPM2A | SIGNOR-276338 |
| AMPK | phosphorylation → up-regulates activity | MCU | SIGNOR-275548 |
| AMPK | phosphorylation → up-regulates | ULK1 | SIGNOR-216457 |
| AMPK | phosphorylation → up-regulates activity | PPARGC1A | SIGNOR-228646 |
| AMPK | phosphorylation → up-regulates activity | PFKFB2 | SIGNOR-216623 |
| AMPK | phosphorylation → up-regulates activity | FOXO | SIGNOR-252885 |
| AMPK | phosphorylation → up-regulates activity | ATG9A | SIGNOR-266365 |
| AMPK | phosphorylation → up-regulates activity | ULK1/Atg13/Fip200 | SIGNOR-209913 |
| AMPK | phosphorylation → up-regulates activity | FOXO | SIGNOR-252882 |
| AMPK | phosphorylation → up-regulates activity | PDHA1 | SIGNOR-277895 |
| AMPK | phosphorylation → down-regulates activity | KCNA5 | SIGNOR-273736 |
| AMPK | phosphorylation down-regulates | VASP | SIGNOR-216568 |
| AMPK | phosphorylation → up-regulates activity | NEDD4L | SIGNOR-276324 |
| AMPK | phosphorylation → down-regulates activity | SLC9A3 | SIGNOR-277849 |
| AMPK | phosphorylation → up-regulates | PFKFB3 | SIGNOR-216639 |