Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
ERK1/2	AP1	Thr325	TELEPLCtPVVTCTP	phosphorylation up-regulates	12972619	SIGNOR-252357

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
ERK1/2	phosphorylation up-regulates →	AP1 PThr325	phosphorylation up-regulates →	AP1	12972619	SIGNOR-252357

Regulator	Mechanism/Effect	Target	SIGNOR-ID
ERK1/2	phosphorylation → up-regulates	AP1	SIGNOR-252357