Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
ERK1/2	AP1	Thr331	CTPVVTCtPSCTAYT	phosphorylation up-regulates	12972619	SIGNOR-252353

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
ERK1/2	phosphorylation up-regulates →	AP1 PThr331	phosphorylation up-regulates →	AP1	12972619	SIGNOR-252353

Regulator	Mechanism/Effect	Target	SIGNOR-ID
ERK1/2	phosphorylation → up-regulates	AP1	SIGNOR-252353