Entity Details

Name CyclinE/CDK2
ID SIGNOR-C16
Role substrate
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1CyclinE/CDK2–phosphorylation
up-regulates		12359725SIGNOR-217499
CDC25ACyclinE/CDK2–dephosphorylation
up-regulates activity		11154267SIGNOR-245452
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
up-regulates 		CyclinE/CDK2SIGNOR-217499
CDC25Adephosphorylation
→
up-regulates activity 		CyclinE/CDK2SIGNOR-245452