| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKA | mTORC2 | – | phosphorylation up-regulates activity | 35065096 | SIGNOR-278149 | |
| mTORC2 | mTORC2 | – | phosphorylation up-regulates activity | 10702316 | SIGNOR-217000 | |
| mTORC2 | mTORC2 | – | phosphorylation up-regulates activity | 20022946 | SIGNOR-235484 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PKA | phosphorylation → up-regulates activity | mTORC2 | SIGNOR-278149 |
| mTORC2 | phosphorylation → up-regulates activity | mTORC2 | SIGNOR-217000 |
| mTORC2 | phosphorylation → up-regulates activity | mTORC2 | SIGNOR-235484 |