Entity Details

Name CyclinY/CDK14
ID SIGNOR-C541
Role kinase
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CyclinY/CDK14LRP6Ser1490AILNPPPsPATERSHphosphorylation
up-regulates activity		24794231SIGNOR-273015
CyclinY/CDK14CCNYSer71RASTIFLsKSQTDVRphosphorylation
down-regulates quantity by destabilization		24794231SIGNOR-273010
CyclinY/CDK14CCNYSer73STIFLSKsQTDVREKphosphorylation
down-regulates quantity by destabilization		24794231SIGNOR-273009
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinY/CDK14phosphorylation
up-regulates
→
LRP6
PSer1490		phosphorylation
up-regulates
→		LRP624794231SIGNOR-273015
CyclinY/CDK14phosphorylation
up-regulates
→
CCNY
PSer71		phosphorylation
down-regulates
⊣		CCNY24794231SIGNOR-273010
CyclinY/CDK14phosphorylation
up-regulates
→
CCNY
PSer73		phosphorylation
down-regulates
⊣		CCNY24794231SIGNOR-273009
Regulator Mechanism/Effect Target SIGNOR-ID
CyclinY/CDK14phosphorylation
→
up-regulates activity 		LRP6SIGNOR-273015
CyclinY/CDK14phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CCNYSIGNOR-273010
CyclinY/CDK14phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CCNYSIGNOR-273009