Entity Details

Name PKA
ID SIGNOR-PF17
Role kinase
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PKAHDAC4Ser584EPGQRQPsEQELLFRphosphorylation
up-regulates activity
30661366SIGNOR-277423
PKACAMKK2Ser495KTMIRKRsFGNPFEGphosphorylation
down-regulates activity
32913128SIGNOR-277238
PKANLRP3Ser295HKIVRKPsRILFLMDphosphorylation
down-regulates activity
27548431SIGNOR-277274
PKAGRK7Ser36ELQRRRRsLALPGLQphosphorylation
down-regulates activity
15946941SIGNOR-260840
PKAKCNA4Thr601LKKFRSStSSSLGDKphosphorylation
down-regulates activity
15955806SIGNOR-273778
PKAMYOM1Ser618ARLKSRPsAPWTGQIphosphorylation
down-regulates activity
9029142SIGNOR-263156
PKAARHGEF6Ser684GSSTRKDsIPQVLLPphosphorylation
down-regulates activity
26507661SIGNOR-272160
PKAPTPN11Ser189GGGERFDsLTDLVEHphosphorylation
down-regulates activity
25802336SIGNOR-276894
PKAGSTA4Ser189QEYTVKLsNIPTIKRphosphorylation
up-regulates activity
12646569SIGNOR-264796
PKASYN1phosphorylation
down-regulates activity
10571231SIGNOR-264108
PKAGRK7Ser23YLQARKPsDCDSKELphosphorylation
down-regulates activity
15946941SIGNOR-276036
PKAATG16L1Ser269RAATKRLsQPAGGLLphosphorylation
down-regulates quantity by destabilization
31580256SIGNOR-277488
PKAGRK1Ser21AFIAARGsFDGSSSQphosphorylation
down-regulates activity
15946941SIGNOR-274079
PKARAP1ASer180KKKPKKKsCLLLphosphorylation
up-regulates activity
17068197SIGNOR-278057
PKACHKBSer39TPKRRRAsSLSRDAEphosphorylation
up-regulates activity
27149373SIGNOR-275632
PKAGRIN2BSer1166SDDFKRDsVSGGGPCphosphorylation
up-regulates activity
24431445SIGNOR-276617
PKAPRKD2Ser706ARIIGEKsFRRSVVGphosphorylation
up-regulates activity
12058027SIGNOR-275952
PKAPPM1BSer195MIQRVNGsLAVSRALphosphorylation
down-regulates quantity by destabilization
23756813SIGNOR-276494
PKACHKBSer40PKRRRASsLSRDAERphosphorylation
up-regulates activity
27149373SIGNOR-275631
PKALIPESer950EGFHPRRsSQGATQMphosphorylation
up-regulates activity
19018281SIGNOR-276174
PKAGLI1Thr374PGCTKRYtDPSSLRKphosphorylation
down-regulates activity
16293631SIGNOR-276044
PKAPIK3R1Ser83YIGRKKIsPPTPKPRphosphorylation
up-regulates activity
21743495SIGNOR-276343
PKAGATA4Ser262IKPQRRLsASRRVGLphosphorylation
up-regulates activity
16109788SIGNOR-276043
PKANOXA1Ser461VPAGPRMsGAPGRLPphosphorylation
down-regulates activity
20943948SIGNOR-264713
PKAPDE4CSer14GEGAEACsRLSRSRGphosphorylation
up-regulates activity
12023945SIGNOR-275987
PKAAQP5Ser156STDSRRTsPVGSPALphosphorylation
up-regulates activity
26569106SIGNOR-272087
PKAARHGAP17Ser702LSAPRRYsSSLSPIQphosphorylation
down-regulates activity
26507661SIGNOR-272156
PKATRPV4Ser162FDIVSRGsTADLDGLphosphorylation
up-regulates activity
19661060SIGNOR-260885
PKABADphosphorylation
down-regulates
10230396SIGNOR-270129
PKAPSMD2Ser361ENNRFGGsGSQVDSAphosphorylation
up-regulates activity
31843888SIGNOR-273898
PKASEC14L2Ser289VQISRGSsHQVEYEIphosphorylation
up-regulates activity
15680919SIGNOR-273788
PKAPIK3CGThr1024YLALRHHtNLLIILFphosphorylation
down-regulates activity
21474070SIGNOR-276321
PKATRPV4Ser189DEEFREPsTGKTCLPphosphorylation
up-regulates activity
19661060SIGNOR-276233
PKAGNMTSer10DSVYRTRsLGVAAEGphosphorylation
unknown
12697024SIGNOR-263151
PKAGATA3Ser308IKPKRRLsAARRAGTphosphorylation
up-regulates activity
16109788SIGNOR-276042
PKAPDE4BSer133GHSQRREsFLYRSDSphosphorylation
up-regulates activity
12023945SIGNOR-273940
PKAPHF2Ser1056FLTQRRPsASSPNNNphosphorylation
up-regulates activity
21532585SIGNOR-264513
PKAIQGAP2Thr716EYMHRRQtFIDNTDSphosphorylation
up-regulates activity
21776420SIGNOR-273742
PKASCN5ASer525TSMKPRSsRGSIFTFphosphorylation
up-regulates activity
33410863SIGNOR-275766
PKAHDAC4phosphorylation
up-regulates activity
30661366SIGNOR-277425
PKANOXA1Ser172DQVQRRGsLPPRQVPphosphorylation
down-regulates activity
20943948SIGNOR-264712
PKAMYBPC3phosphorylation
up-regulates
20151718SIGNOR-270128
PKAGRK1Ser21AFIAARGsFDGSSSQphosphorylation
down-regulates activity
15946941SIGNOR-276034
PKAmTORC2phosphorylation
up-regulates activity
35065096SIGNOR-278149
PKATRPC5Ser796GARAKSKsVSFNLGCphosphorylation
down-regulates quantity
21734191SIGNOR-277824
PKANKD2Ser223SAHVRRPsTDPQPCSphosphorylation
up-regulates quantity by stabilization
30941853SIGNOR-273782
PKAHSPB8Ser24RRDPFRDsPLSSRLLphosphorylation
down-regulates quantity by destabilization
18298377SIGNOR-276152
PKATRPV4Thr175GLLPFLLtHKKRLTDphosphorylation
up-regulates activity
19661060SIGNOR-276231
PKASCN5ASer528KPRSSRGsIFTFRRRphosphorylation
up-regulates activity
12242273SIGNOR-275992
PKAPDE8ASer359HKDRRKGsLDVKAVAphosphorylation
up-regulates activity
22673573SIGNOR-273783
PKAABCC8phosphorylation
down-regulates activity
35065096SIGNOR-278146
PKAABCC8phosphorylation
down-regulates activity
35065096SIGNOR-278147
PKACAMKK2Ser100HLSGRKLsLQERSQGphosphorylation
down-regulates activity
32913128SIGNOR-277239
PKAFRAT1Ser188RLQQRRGsQPETRTGphosphorylation
down-regulates activity
16982607SIGNOR-276058
PKASNAI2Ser247KYQCKNCsKTFSRMSphosphorylation
down-regulates quantity by destabilization
37596321SIGNOR-277905
PKAKCNA4Thr601LKKFRSStSSSLGDKphosphorylation
down-regulates quantity by destabilization
15955806SIGNOR-276037
PKAKLHL3Ser433PMNTRRSsVGVGVVEphosphorylation
up-regulates activity
26435498SIGNOR-273824
PKAGRK1Ser21AFIAARGsFDGSSSQphosphorylation
down-regulates activity
15946941SIGNOR-260841
PKAMOSSer73LGAGGFGsVYKATYRphosphorylation
down-regulates activity
8622681SIGNOR-260819
PKATRPV4Ser189DEEFREPsTGKTCLPphosphorylation
up-regulates activity
19661060SIGNOR-260883
PKACAMKK2Ser511RREERSLsAPGNLLTphosphorylation
down-regulates activity
32913128SIGNOR-277240
PKASYN2phosphorylation
down-regulates activity
10571231SIGNOR-264109
PKAMFN2Ser442AEEIRRLSVLVDDYQphosphorylation
up-regulates activity
20303493SIGNOR-274137
PKASISer7sGLEISLIphosphorylation
unknown
8521865SIGNOR-263157
PKAPDE4BSer133GHSQRREsFLYRSDSphosphorylation
up-regulates activity
12023945SIGNOR-275986
PKAEVLphosphorylation
up-regulates activity
15066263SIGNOR-268287
PKACAMKK2Ser100HLSGRKLsLQERSQGphosphorylation
down-regulates
22778263SIGNOR-198146
PKASLITRK1Ser695DCGSHSLsDphosphorylation
up-regulates activity
19640509SIGNOR-273634
PKAPDZK1Ser505MAKERAHsTASHSSSphosphorylation
up-regulates activity
16174736SIGNOR-273784
PKASLC4A4Ser1026KKKKKKGsLDSDNDDphosphorylation
up-regulates activity
11744745SIGNOR-263158
PKAPDE4ASer89TRMSWPSsFHGTGTGphosphorylation
up-regulates activity
12023945SIGNOR-273937
PKAGRK7Ser23YLQARKPsDCDSKELphosphorylation
down-regulates activity
15946941SIGNOR-260839
PKAPDE11ASer117GNLQRRAsQKELRKSphosphorylation
up-regulates activity
18312413SIGNOR-276153
PKAPHKA1phosphorylation
down-regulates activity
10487978SIGNOR-267409
PKACREB1Ser119EILSRRPsYRKILNDphosphorylation
up-regulates activity
8386317SIGNOR-263653
PKAPHF2Ser757NARVKKEsGSSAAGIphosphorylation
up-regulates activity
21532585SIGNOR-264510
PKASLC9A3Ser555AEGERRGsLAFIRSPphosphorylation
down-regulates activity
38047302SIGNOR-277847
PKAPDE4DSer125CRAMDRTsYAVETGHphosphorylation
up-regulates activity
12023945SIGNOR-273939
PKAPRKD2Ser710GEKSFRRsVVGTPAYphosphorylation
up-regulates activity
12058027SIGNOR-275951
PKAATG16L1Ser268SRAATRRsVSSFPVPphosphorylation
down-regulates quantity by destabilization
31580256SIGNOR-277489
PKAHSPB8Ser57DWALPRLsSAWPGTLphosphorylation
down-regulates quantity by destabilization
18298377SIGNOR-276151
PKASYN3phosphorylation
down-regulates activity
10571231SIGNOR-264110
PKATRPC5Ser796GARAKSKsVSFNLGCphosphorylation
down-regulates activity
21734191SIGNOR-276339
PKATRPC5Ser794SGGARAKsKSVSFNLphosphorylation
down-regulates activity
21734191SIGNOR-276340
PKAPDE4ASer145ATSQRREsFLYRSDSphosphorylation
up-regulates activity
12023945SIGNOR-275985
PKAGRK7Ser36ELQRRRRsLALPGLQphosphorylation
down-regulates activity
15946941SIGNOR-276035
PKASCN5ASer36AEKQARGsTTLQESRphosphorylation
up-regulates activity
33410863SIGNOR-275765
PKALIPESer951GFHPRRSsQGATQMPphosphorylation
up-regulates activity
19018281SIGNOR-276175
PKAKCNJ2Ser425PRPLRREsEIphosphorylation
down-regulates activity
19843922SIGNOR-273779
PKACAMKK2Ser511RREERSLsAPGNLLTphosphorylation
down-regulates
22778263SIGNOR-198154
PKAPPP1R1BThr34MIRRRRPtPAMLFRLphosphorylation
up-regulates activity
10604473SIGNOR-264956
PKASCN5ASer528KPRSSRGsIFTFRRRphosphorylation
up-regulates activity
33410863SIGNOR-275764
PKATRPC5Ser794SGGARAKsKSVSFNLphosphorylation
down-regulates activity
21734191SIGNOR-273790
PKATRPV4Ser162FDIVSRGsTADLDGLphosphorylation
up-regulates activity
19661060SIGNOR-276232
PKAPHF2Ser954QKSKKKKsAKRKLTPphosphorylation
up-regulates activity
21532585SIGNOR-264512
PKAGABA-Aphosphorylation
up-regulates quantity
25600368SIGNOR-264991
PKAPRKD2Ser876QGLAERIsVLphosphorylation
up-regulates activity
12058027SIGNOR-275950
PKADIAPH1Thr768PVLPFGLtPKKLYKPphosphorylation
up-regulates quantity by stabilization
23325789SIGNOR-276484
PKAKCNA1Ser446SDLSRRSsSTMSKSEphosphorylation
down-regulates quantity
23774215SIGNOR-273777
PKAPRKD3Ser731ARIIGEKsFRRSVVGphosphorylation
up-regulates activity
18692497SIGNOR-275924
PKAPDE8ASer359HKDRRKGsLDVKAVAphosphorylation
up-regulates activity
22673573SIGNOR-276416
PKATRPC5Ser796GARAKSKsVSFNLGCphosphorylation
down-regulates activity
21734191SIGNOR-273789
PKAGAD1Thr91RDARFRRtETDFSNLphosphorylation
down-regulates activity
15147202SIGNOR-276009
PKAKCNJ4Ser443NISYRREsAIphosphorylation
up-regulates activity
19635485SIGNOR-263153
PKADNM1LSer637VPVARKLsAREQRDCphosphorylation
down-regulates activity
31063459SIGNOR-262551
PKASCN2Aphosphorylation
down-regulates activity
32599005SIGNOR-275749
PKAPDE4DSer125CRAMDRTsYAVETGHphosphorylation
up-regulates activity
12023945SIGNOR-275988
PKATRPV4Thr175GLLPFLLtHKKRLTDphosphorylation
up-regulates activity
19661060SIGNOR-260881
PKALRP6Thr1548YAPSRRMtSVATAKGphosphorylation
up-regulates activity
21406690SIGNOR-275416
PKAGSK3BSer9SGRPRTTsFAESCKPphosphorylation
down-regulates activity
26088133SIGNOR-264819
PKAPHKA2phosphorylation
down-regulates activity
10487978SIGNOR-267408
PKASEC14L2Ser289VQISRGSsHQVEYEIphosphorylation
up-regulates activity
15680919SIGNOR-276028
PKAARHGEF6Ser640RKTERKPsEEEYVIRphosphorylation
down-regulates activity
26507661SIGNOR-272163
PKATENT2phosphorylation
down-regulates activity
31057087SIGNOR-270130
PKACADSer1406GAGGRRLsSFVTKGYphosphorylation
down-regulates activity
17485345SIGNOR-267442
PKANR5A2Ser510LPEIRAIsMQAEEYLphosphorylation
up-regulates activity
16109788SIGNOR-276041
PKAPDE11ASer162RALLRKAsSLPPTTAphosphorylation
up-regulates activity
18312413SIGNOR-276179
PKACDK18Ser14KNFKRRFsLSVPRTEphosphorylation
up-regulates activity
28361970SIGNOR-264559
PKAPTPN11Thr73YGGEKFAtLAELVQYphosphorylation
down-regulates activity
25802336SIGNOR-276893
PKAGRK7Ser23YLQARKPsDCDSKELphosphorylation
down-regulates activity
15946941SIGNOR-274081
PKAAQP2Ser256REVRRRQsVELHSPQphosphorylation
up-regulates activity
12194985SIGNOR-264563
PKASMN1phosphorylation
up-regulates quantity by stabilization
19103745SIGNOR-253114
PKAHDAC4phosphorylation
up-regulates activity
30661366SIGNOR-277424
PKABRSK2Thr260VDAARRLtLEHIQKHphosphorylation
up-regulates activity
16870137SIGNOR-276056
PKASMN complexphosphorylation
up-regulates quantity by stabilization
19103745SIGNOR-253122
PKASLC2A2Ser491VPETKGKsFEEIAAEphosphorylation
down-regulates activity
8626492SIGNOR-250049
PKAPRKD1Ser742GEKSFRRsVVGTPAYphosphorylation
up-regulates activity
18692497SIGNOR-275925
PKACAMKK2Ser495KTMIRKRsFGNPFEGphosphorylation
down-regulates
22778263SIGNOR-198150
PKAPHF2Ser899RSKKRKGsDDAPYSPphosphorylation
up-regulates activity
21532585SIGNOR-264511
PKAGRK7Ser36ELQRRRRsLALPGLQphosphorylation
down-regulates activity
15946941SIGNOR-274080
PKAKCNK18Ser252QAMERSNsCPELVLGphosphorylation
down-regulates activity
18397886SIGNOR-263154
PKASLC8B1Ser258YQRQRRGsLFCPMPVphosphorylation
up-regulates activity
36476859SIGNOR-275728
PKAGRK7Ser36ELQRRRRsLALPGLQphosphorylation
up-regulates activity
18803695SIGNOR-263152
PKAENAHphosphorylation
up-regulates activity
15066263SIGNOR-268285
PKASCN5ASer525TSMKPRSsRGSIFTFphosphorylation
up-regulates activity
12242273SIGNOR-275991
PKAPPM1BSer195MIQRVNGsLAVSRALphosphorylation
down-regulates quantity by destabilization
23756813SIGNOR-277825
PKAPDE4CSer14GEGAEACsRLSRSRGphosphorylation
up-regulates activity
12023945SIGNOR-273938
PKAVASPphosphorylation
up-regulates activity
15066263SIGNOR-268286
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PKAphosphorylation
up-regulates
HDAC4
PSer584
phosphorylation
up-regulates
HDAC430661366SIGNOR-277423
PKAphosphorylation
up-regulates
CAMKK2
PSer495
phosphorylation
down-regulates
CAMKK232913128SIGNOR-277238
PKAphosphorylation
up-regulates
NLRP3
PSer295
phosphorylation
down-regulates
NLRP327548431SIGNOR-277274
PKAphosphorylation
up-regulates
GRK7
PSer36
phosphorylation
down-regulates
GRK715946941SIGNOR-260840
PKAphosphorylation
up-regulates
KCNA4
PThr601
phosphorylation
down-regulates
KCNA415955806SIGNOR-273778
PKAphosphorylation
up-regulates
MYOM1
PSer618
phosphorylation
down-regulates
MYOM19029142SIGNOR-263156
PKAphosphorylation
up-regulates
ARHGEF6
PSer684
phosphorylation
down-regulates
ARHGEF626507661SIGNOR-272160
PKAphosphorylation
up-regulates
PTPN11
PSer189
phosphorylation
down-regulates
PTPN1125802336SIGNOR-276894
PKAphosphorylation
up-regulates
GSTA4
PSer189
phosphorylation
up-regulates
GSTA412646569SIGNOR-264796
PKAphosphorylation
up-regulates
GRK7
PSer23
phosphorylation
down-regulates
GRK715946941SIGNOR-276036
PKAphosphorylation
up-regulates
ATG16L1
PSer269
phosphorylation
down-regulates
ATG16L131580256SIGNOR-277488
PKAphosphorylation
up-regulates
GRK1
PSer21
phosphorylation
down-regulates
GRK115946941SIGNOR-274079
PKAphosphorylation
up-regulates
RAP1A
PSer180
phosphorylation
up-regulates
RAP1A17068197SIGNOR-278057
PKAphosphorylation
up-regulates
CHKB
PSer39
phosphorylation
up-regulates
CHKB27149373SIGNOR-275632
PKAphosphorylation
up-regulates
GRIN2B
PSer1166
phosphorylation
up-regulates
GRIN2B24431445SIGNOR-276617
PKAphosphorylation
up-regulates
PRKD2
PSer706
phosphorylation
up-regulates
PRKD212058027SIGNOR-275952
PKAphosphorylation
up-regulates
PPM1B
PSer195
phosphorylation
down-regulates
PPM1B23756813SIGNOR-276494
PKAphosphorylation
up-regulates
CHKB
PSer40
phosphorylation
up-regulates
CHKB27149373SIGNOR-275631
PKAphosphorylation
up-regulates
LIPE
PSer950
phosphorylation
up-regulates
LIPE19018281SIGNOR-276174
PKAphosphorylation
up-regulates
GLI1
PThr374
phosphorylation
down-regulates
GLI116293631SIGNOR-276044
PKAphosphorylation
up-regulates
PIK3R1
PSer83
phosphorylation
up-regulates
PIK3R121743495SIGNOR-276343
PKAphosphorylation
up-regulates
GATA4
PSer262
phosphorylation
up-regulates
GATA416109788SIGNOR-276043
PKAphosphorylation
up-regulates
NOXA1
PSer461
phosphorylation
down-regulates
NOXA120943948SIGNOR-264713
PKAphosphorylation
up-regulates
PDE4C
PSer14
phosphorylation
up-regulates
PDE4C12023945SIGNOR-275987
PKAphosphorylation
up-regulates
AQP5
PSer156
phosphorylation
up-regulates
AQP526569106SIGNOR-272087
PKAphosphorylation
up-regulates
ARHGAP17
PSer702
phosphorylation
down-regulates
ARHGAP1726507661SIGNOR-272156
PKAphosphorylation
up-regulates
TRPV4
PSer162
phosphorylation
up-regulates
TRPV419661060SIGNOR-260885
PKAphosphorylation
up-regulates
PSMD2
PSer361
phosphorylation
up-regulates
PSMD231843888SIGNOR-273898
PKAphosphorylation
up-regulates
SEC14L2
PSer289
phosphorylation
up-regulates
SEC14L215680919SIGNOR-273788
PKAphosphorylation
up-regulates
PIK3CG
PThr1024
phosphorylation
down-regulates
PIK3CG21474070SIGNOR-276321
PKAphosphorylation
up-regulates
TRPV4
PSer189
phosphorylation
up-regulates
TRPV419661060SIGNOR-276233
PKAphosphorylation
up-regulates
GNMT
PSer10
phosphorylation
down-regulates
GNMT12697024SIGNOR-263151
PKAphosphorylation
up-regulates
GATA3
PSer308
phosphorylation
up-regulates
GATA316109788SIGNOR-276042
PKAphosphorylation
up-regulates
PDE4B
PSer133
phosphorylation
up-regulates
PDE4B12023945SIGNOR-273940
PKAphosphorylation
up-regulates
PHF2
PSer1056
phosphorylation
up-regulates
PHF221532585SIGNOR-264513
PKAphosphorylation
up-regulates
IQGAP2
PThr716
phosphorylation
up-regulates
IQGAP221776420SIGNOR-273742
PKAphosphorylation
up-regulates
SCN5A
PSer525
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275766
PKAphosphorylation
up-regulates
NOXA1
PSer172
phosphorylation
down-regulates
NOXA120943948SIGNOR-264712
PKAphosphorylation
up-regulates
GRK1
PSer21
phosphorylation
down-regulates
GRK115946941SIGNOR-276034
PKAphosphorylation
up-regulates
TRPC5
PSer796
phosphorylation
down-regulates
TRPC521734191SIGNOR-277824
PKAphosphorylation
up-regulates
NKD2
PSer223
phosphorylation
up-regulates
NKD230941853SIGNOR-273782
PKAphosphorylation
up-regulates
HSPB8
PSer24
phosphorylation
down-regulates
HSPB818298377SIGNOR-276152
PKAphosphorylation
up-regulates
TRPV4
PThr175
phosphorylation
up-regulates
TRPV419661060SIGNOR-276231
PKAphosphorylation
up-regulates
SCN5A
PSer528
phosphorylation
up-regulates
SCN5A12242273SIGNOR-275992
PKAphosphorylation
up-regulates
PDE8A
PSer359
phosphorylation
up-regulates
PDE8A22673573SIGNOR-273783
PKAphosphorylation
up-regulates
CAMKK2
PSer100
phosphorylation
down-regulates
CAMKK232913128SIGNOR-277239
PKAphosphorylation
up-regulates
FRAT1
PSer188
phosphorylation
down-regulates
FRAT116982607SIGNOR-276058
PKAphosphorylation
up-regulates
SNAI2
PSer247
phosphorylation
down-regulates
SNAI237596321SIGNOR-277905
PKAphosphorylation
up-regulates
KCNA4
PThr601
phosphorylation
down-regulates
KCNA415955806SIGNOR-276037
PKAphosphorylation
up-regulates
KLHL3
PSer433
phosphorylation
up-regulates
KLHL326435498SIGNOR-273824
PKAphosphorylation
up-regulates
GRK1
PSer21
phosphorylation
down-regulates
GRK115946941SIGNOR-260841
PKAphosphorylation
up-regulates
MOS
PSer73
phosphorylation
down-regulates
MOS8622681SIGNOR-260819
PKAphosphorylation
up-regulates
TRPV4
PSer189
phosphorylation
up-regulates
TRPV419661060SIGNOR-260883
PKAphosphorylation
up-regulates
CAMKK2
PSer511
phosphorylation
down-regulates
CAMKK232913128SIGNOR-277240
PKAphosphorylation
up-regulates
MFN2
PSer442
phosphorylation
up-regulates
MFN220303493SIGNOR-274137
PKAphosphorylation
up-regulates
SI
PSer7
phosphorylation
down-regulates
SI8521865SIGNOR-263157
PKAphosphorylation
up-regulates
PDE4B
PSer133
phosphorylation
up-regulates
PDE4B12023945SIGNOR-275986
PKAphosphorylation
up-regulates
CAMKK2
PSer100
phosphorylation
down-regulates
CAMKK222778263SIGNOR-198146
PKAphosphorylation
up-regulates
SLITRK1
PSer695
phosphorylation
up-regulates
SLITRK119640509SIGNOR-273634
PKAphosphorylation
up-regulates
PDZK1
PSer505
phosphorylation
up-regulates
PDZK116174736SIGNOR-273784
PKAphosphorylation
up-regulates
SLC4A4
PSer1026
phosphorylation
up-regulates
SLC4A411744745SIGNOR-263158
PKAphosphorylation
up-regulates
PDE4A
PSer89
phosphorylation
up-regulates
PDE4A12023945SIGNOR-273937
PKAphosphorylation
up-regulates
GRK7
PSer23
phosphorylation
down-regulates
GRK715946941SIGNOR-260839
PKAphosphorylation
up-regulates
PDE11A
PSer117
phosphorylation
up-regulates
PDE11A18312413SIGNOR-276153
PKAphosphorylation
up-regulates
CREB1
PSer119
phosphorylation
up-regulates
CREB18386317SIGNOR-263653
PKAphosphorylation
up-regulates
PHF2
PSer757
phosphorylation
up-regulates
PHF221532585SIGNOR-264510
PKAphosphorylation
up-regulates
SLC9A3
PSer555
phosphorylation
down-regulates
SLC9A338047302SIGNOR-277847
PKAphosphorylation
up-regulates
PDE4D
PSer125
phosphorylation
up-regulates
PDE4D12023945SIGNOR-273939
PKAphosphorylation
up-regulates
PRKD2
PSer710
phosphorylation
up-regulates
PRKD212058027SIGNOR-275951
PKAphosphorylation
up-regulates
ATG16L1
PSer268
phosphorylation
down-regulates
ATG16L131580256SIGNOR-277489
PKAphosphorylation
up-regulates
HSPB8
PSer57
phosphorylation
down-regulates
HSPB818298377SIGNOR-276151
PKAphosphorylation
up-regulates
TRPC5
PSer796
phosphorylation
down-regulates
TRPC521734191SIGNOR-276339
PKAphosphorylation
up-regulates
TRPC5
PSer794
phosphorylation
down-regulates
TRPC521734191SIGNOR-276340
PKAphosphorylation
up-regulates
PDE4A
PSer145
phosphorylation
up-regulates
PDE4A12023945SIGNOR-275985
PKAphosphorylation
up-regulates
GRK7
PSer36
phosphorylation
down-regulates
GRK715946941SIGNOR-276035
PKAphosphorylation
up-regulates
SCN5A
PSer36
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275765
PKAphosphorylation
up-regulates
LIPE
PSer951
phosphorylation
up-regulates
LIPE19018281SIGNOR-276175
PKAphosphorylation
up-regulates
KCNJ2
PSer425
phosphorylation
down-regulates
KCNJ219843922SIGNOR-273779
PKAphosphorylation
up-regulates
CAMKK2
PSer511
phosphorylation
down-regulates
CAMKK222778263SIGNOR-198154
PKAphosphorylation
up-regulates
PPP1R1B
PThr34
phosphorylation
up-regulates
PPP1R1B10604473SIGNOR-264956
PKAphosphorylation
up-regulates
SCN5A
PSer528
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275764
PKAphosphorylation
up-regulates
TRPC5
PSer794
phosphorylation
down-regulates
TRPC521734191SIGNOR-273790
PKAphosphorylation
up-regulates
TRPV4
PSer162
phosphorylation
up-regulates
TRPV419661060SIGNOR-276232
PKAphosphorylation
up-regulates
PHF2
PSer954
phosphorylation
up-regulates
PHF221532585SIGNOR-264512
PKAphosphorylation
up-regulates
PRKD2
PSer876
phosphorylation
up-regulates
PRKD212058027SIGNOR-275950
PKAphosphorylation
up-regulates
DIAPH1
PThr768
phosphorylation
up-regulates
DIAPH123325789SIGNOR-276484
PKAphosphorylation
up-regulates
KCNA1
PSer446
phosphorylation
down-regulates
KCNA123774215SIGNOR-273777
PKAphosphorylation
up-regulates
PRKD3
PSer731
phosphorylation
up-regulates
PRKD318692497SIGNOR-275924
PKAphosphorylation
up-regulates
PDE8A
PSer359
phosphorylation
up-regulates
PDE8A22673573SIGNOR-276416
PKAphosphorylation
up-regulates
TRPC5
PSer796
phosphorylation
down-regulates
TRPC521734191SIGNOR-273789
PKAphosphorylation
up-regulates
GAD1
PThr91
phosphorylation
down-regulates
GAD115147202SIGNOR-276009
PKAphosphorylation
up-regulates
KCNJ4
PSer443
phosphorylation
up-regulates
KCNJ419635485SIGNOR-263153
PKAphosphorylation
up-regulates
DNM1L
PSer637
phosphorylation
down-regulates
DNM1L31063459SIGNOR-262551
PKAphosphorylation
up-regulates
PDE4D
PSer125
phosphorylation
up-regulates
PDE4D12023945SIGNOR-275988
PKAphosphorylation
up-regulates
TRPV4
PThr175
phosphorylation
up-regulates
TRPV419661060SIGNOR-260881
PKAphosphorylation
up-regulates
LRP6
PThr1548
phosphorylation
up-regulates
LRP621406690SIGNOR-275416
PKAphosphorylation
up-regulates
GSK3B
PSer9
phosphorylation
down-regulates
GSK3B26088133SIGNOR-264819
PKAphosphorylation
up-regulates
SEC14L2
PSer289
phosphorylation
up-regulates
SEC14L215680919SIGNOR-276028
PKAphosphorylation
up-regulates
ARHGEF6
PSer640
phosphorylation
down-regulates
ARHGEF626507661SIGNOR-272163
PKAphosphorylation
up-regulates
CAD
PSer1406
phosphorylation
down-regulates
CAD17485345SIGNOR-267442
PKAphosphorylation
up-regulates
NR5A2
PSer510
phosphorylation
up-regulates
NR5A216109788SIGNOR-276041
PKAphosphorylation
up-regulates
PDE11A
PSer162
phosphorylation
up-regulates
PDE11A18312413SIGNOR-276179
PKAphosphorylation
up-regulates
CDK18
PSer14
phosphorylation
up-regulates
CDK1828361970SIGNOR-264559
PKAphosphorylation
up-regulates
PTPN11
PThr73
phosphorylation
down-regulates
PTPN1125802336SIGNOR-276893
PKAphosphorylation
up-regulates
GRK7
PSer23
phosphorylation
down-regulates
GRK715946941SIGNOR-274081
PKAphosphorylation
up-regulates
AQP2
PSer256
phosphorylation
up-regulates
AQP212194985SIGNOR-264563
PKAphosphorylation
up-regulates
BRSK2
PThr260
phosphorylation
up-regulates
BRSK216870137SIGNOR-276056
PKAphosphorylation
up-regulates
SLC2A2
PSer491
phosphorylation
down-regulates
SLC2A28626492SIGNOR-250049
PKAphosphorylation
up-regulates
PRKD1
PSer742
phosphorylation
up-regulates
PRKD118692497SIGNOR-275925
PKAphosphorylation
up-regulates
CAMKK2
PSer495
phosphorylation
down-regulates
CAMKK222778263SIGNOR-198150
PKAphosphorylation
up-regulates
PHF2
PSer899
phosphorylation
up-regulates
PHF221532585SIGNOR-264511
PKAphosphorylation
up-regulates
GRK7
PSer36
phosphorylation
down-regulates
GRK715946941SIGNOR-274080
PKAphosphorylation
up-regulates
KCNK18
PSer252
phosphorylation
down-regulates
KCNK1818397886SIGNOR-263154
PKAphosphorylation
up-regulates
SLC8B1
PSer258
phosphorylation
up-regulates
SLC8B136476859SIGNOR-275728
PKAphosphorylation
up-regulates
GRK7
PSer36
phosphorylation
up-regulates
GRK718803695SIGNOR-263152
PKAphosphorylation
up-regulates
SCN5A
PSer525
phosphorylation
up-regulates
SCN5A12242273SIGNOR-275991
PKAphosphorylation
up-regulates
PPM1B
PSer195
phosphorylation
down-regulates
PPM1B23756813SIGNOR-277825
PKAphosphorylation
up-regulates
PDE4C
PSer14
phosphorylation
up-regulates
PDE4C12023945SIGNOR-273938
Regulator Mechanism/Effect Target SIGNOR-ID
PKAphosphorylation

up-regulates activity
HDAC4SIGNOR-277423
PKAphosphorylation

down-regulates activity
CAMKK2SIGNOR-277238
PKAphosphorylation

down-regulates activity
NLRP3SIGNOR-277274
PKAphosphorylation

down-regulates activity
GRK7SIGNOR-260840
PKAphosphorylation

down-regulates activity
KCNA4SIGNOR-273778
PKAphosphorylation

down-regulates activity
MYOM1SIGNOR-263156
PKAphosphorylation

down-regulates activity
ARHGEF6SIGNOR-272160
PKAphosphorylation

down-regulates activity
PTPN11SIGNOR-276894
PKAphosphorylation

up-regulates activity
GSTA4SIGNOR-264796
PKAphosphorylation

down-regulates activity
SYN1SIGNOR-264108
PKAphosphorylation

down-regulates activity
GRK7SIGNOR-276036
PKAphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
ATG16L1SIGNOR-277488
PKAphosphorylation

down-regulates activity
GRK1SIGNOR-274079
PKAphosphorylation

up-regulates activity
RAP1ASIGNOR-278057
PKAphosphorylation

up-regulates activity
CHKBSIGNOR-275632
PKAphosphorylation

up-regulates activity
GRIN2BSIGNOR-276617
PKAphosphorylation

up-regulates activity
PRKD2SIGNOR-275952
PKAphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
PPM1BSIGNOR-276494
PKAphosphorylation

up-regulates activity
CHKBSIGNOR-275631
PKAphosphorylation

up-regulates activity
LIPESIGNOR-276174
PKAphosphorylation

down-regulates activity
GLI1SIGNOR-276044
PKAphosphorylation

up-regulates activity
PIK3R1SIGNOR-276343
PKAphosphorylation

up-regulates activity
GATA4SIGNOR-276043
PKAphosphorylation

down-regulates activity
NOXA1SIGNOR-264713
PKAphosphorylation

up-regulates activity
PDE4CSIGNOR-275987
PKAphosphorylation

up-regulates activity
AQP5SIGNOR-272087
PKAphosphorylation

down-regulates activity
ARHGAP17SIGNOR-272156
PKAphosphorylation

up-regulates activity
TRPV4SIGNOR-260885
PKAphosphorylation
img/direct_inhibition.png
down-regulates
BADSIGNOR-270129
PKAphosphorylation

up-regulates activity
PSMD2SIGNOR-273898
PKAphosphorylation

up-regulates activity
SEC14L2SIGNOR-273788
PKAphosphorylation

down-regulates activity
PIK3CGSIGNOR-276321
PKAphosphorylation

up-regulates activity
TRPV4SIGNOR-276233
PKAphosphorylation

unknown
GNMTSIGNOR-263151
PKAphosphorylation

up-regulates activity
GATA3SIGNOR-276042
PKAphosphorylation

up-regulates activity
PDE4BSIGNOR-273940
PKAphosphorylation

up-regulates activity
PHF2SIGNOR-264513
PKAphosphorylation

up-regulates activity
IQGAP2SIGNOR-273742
PKAphosphorylation

up-regulates activity
SCN5ASIGNOR-275766
PKAphosphorylation

up-regulates activity
HDAC4SIGNOR-277425
PKAphosphorylation

down-regulates activity
NOXA1SIGNOR-264712
PKAphosphorylation

up-regulates
MYBPC3SIGNOR-270128
PKAphosphorylation

down-regulates activity
GRK1SIGNOR-276034
PKAphosphorylation

up-regulates activity
mTORC2SIGNOR-278149
PKAphosphorylation

down-regulates quantity
TRPC5SIGNOR-277824
PKAphosphorylation

up-regulates quantity by stabilization
NKD2SIGNOR-273782
PKAphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
HSPB8SIGNOR-276152
PKAphosphorylation

up-regulates activity
TRPV4SIGNOR-276231
PKAphosphorylation

up-regulates activity
SCN5ASIGNOR-275992
PKAphosphorylation

up-regulates activity
PDE8ASIGNOR-273783
PKAphosphorylation

down-regulates activity
ABCC8SIGNOR-278146
PKAphosphorylation

down-regulates activity
ABCC8SIGNOR-278147
PKAphosphorylation

down-regulates activity
CAMKK2SIGNOR-277239
PKAphosphorylation

down-regulates activity
FRAT1SIGNOR-276058
PKAphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
SNAI2SIGNOR-277905
PKAphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
KCNA4SIGNOR-276037
PKAphosphorylation

up-regulates activity
KLHL3SIGNOR-273824
PKAphosphorylation

down-regulates activity
GRK1SIGNOR-260841
PKAphosphorylation

down-regulates activity
MOSSIGNOR-260819
PKAphosphorylation

up-regulates activity
TRPV4SIGNOR-260883
PKAphosphorylation

down-regulates activity
CAMKK2SIGNOR-277240
PKAphosphorylation

down-regulates activity
SYN2SIGNOR-264109
PKAphosphorylation

up-regulates activity
MFN2SIGNOR-274137
PKAphosphorylation

unknown
SISIGNOR-263157
PKAphosphorylation

up-regulates activity
PDE4BSIGNOR-275986
PKAphosphorylation

up-regulates activity
EVLSIGNOR-268287
PKAphosphorylation
img/direct_inhibition.png
down-regulates
CAMKK2SIGNOR-198146
PKAphosphorylation

up-regulates activity
SLITRK1SIGNOR-273634
PKAphosphorylation

up-regulates activity
PDZK1SIGNOR-273784
PKAphosphorylation

up-regulates activity
SLC4A4SIGNOR-263158
PKAphosphorylation

up-regulates activity
PDE4ASIGNOR-273937
PKAphosphorylation

down-regulates activity
GRK7SIGNOR-260839
PKAphosphorylation

up-regulates activity
PDE11ASIGNOR-276153
PKAphosphorylation

down-regulates activity
PHKA1SIGNOR-267409
PKAphosphorylation

up-regulates activity
CREB1SIGNOR-263653
PKAphosphorylation

up-regulates activity
PHF2SIGNOR-264510
PKAphosphorylation

down-regulates activity
SLC9A3SIGNOR-277847
PKAphosphorylation

up-regulates activity
PDE4DSIGNOR-273939
PKAphosphorylation

up-regulates activity
PRKD2SIGNOR-275951
PKAphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
ATG16L1SIGNOR-277489
PKAphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
HSPB8SIGNOR-276151
PKAphosphorylation

down-regulates activity
SYN3SIGNOR-264110
PKAphosphorylation

down-regulates activity
TRPC5SIGNOR-276339
PKAphosphorylation

down-regulates activity
TRPC5SIGNOR-276340
PKAphosphorylation

up-regulates activity
PDE4ASIGNOR-275985
PKAphosphorylation

down-regulates activity
GRK7SIGNOR-276035
PKAphosphorylation

up-regulates activity
SCN5ASIGNOR-275765
PKAphosphorylation

up-regulates activity
LIPESIGNOR-276175
PKAphosphorylation

down-regulates activity
KCNJ2SIGNOR-273779
PKAphosphorylation
img/direct_inhibition.png
down-regulates
CAMKK2SIGNOR-198154
PKAphosphorylation

up-regulates activity
PPP1R1BSIGNOR-264956
PKAphosphorylation

up-regulates activity
SCN5ASIGNOR-275764
PKAphosphorylation

down-regulates activity
TRPC5SIGNOR-273790
PKAphosphorylation

up-regulates activity
TRPV4SIGNOR-276232
PKAphosphorylation

up-regulates activity
PHF2SIGNOR-264512
PKAphosphorylation

up-regulates quantity
GABA-ASIGNOR-264991
PKAphosphorylation

up-regulates activity
PRKD2SIGNOR-275950
PKAphosphorylation

up-regulates quantity by stabilization
DIAPH1SIGNOR-276484
PKAphosphorylation

down-regulates quantity
KCNA1SIGNOR-273777
PKAphosphorylation

up-regulates activity
PRKD3SIGNOR-275924
PKAphosphorylation

up-regulates activity
PDE8ASIGNOR-276416
PKAphosphorylation

down-regulates activity
TRPC5SIGNOR-273789
PKAphosphorylation

down-regulates activity
GAD1SIGNOR-276009
PKAphosphorylation

up-regulates activity
KCNJ4SIGNOR-263153
PKAphosphorylation

down-regulates activity
DNM1LSIGNOR-262551
PKAphosphorylation

down-regulates activity
SCN2ASIGNOR-275749
PKAphosphorylation

up-regulates activity
PDE4DSIGNOR-275988
PKAphosphorylation

up-regulates activity
TRPV4SIGNOR-260881
PKAphosphorylation

up-regulates activity
LRP6SIGNOR-275416
PKAphosphorylation

down-regulates activity
GSK3BSIGNOR-264819
PKAphosphorylation

down-regulates activity
PHKA2SIGNOR-267408
PKAphosphorylation

up-regulates activity
SEC14L2SIGNOR-276028
PKAphosphorylation

down-regulates activity
ARHGEF6SIGNOR-272163
PKAphosphorylation

down-regulates activity
TENT2SIGNOR-270130
PKAphosphorylation

down-regulates activity
CADSIGNOR-267442
PKAphosphorylation

up-regulates activity
NR5A2SIGNOR-276041
PKAphosphorylation

up-regulates activity
PDE11ASIGNOR-276179
PKAphosphorylation

up-regulates activity
CDK18SIGNOR-264559
PKAphosphorylation

down-regulates activity
PTPN11SIGNOR-276893
PKAphosphorylation

down-regulates activity
GRK7SIGNOR-274081
PKAphosphorylation

up-regulates activity
AQP2SIGNOR-264563
PKAphosphorylation

up-regulates quantity by stabilization
SMN1SIGNOR-253114
PKAphosphorylation

up-regulates activity
HDAC4SIGNOR-277424
PKAphosphorylation

up-regulates activity
BRSK2SIGNOR-276056
PKAphosphorylation

up-regulates quantity by stabilization
SMN complexSIGNOR-253122
PKAphosphorylation

down-regulates activity
SLC2A2SIGNOR-250049
PKAphosphorylation

up-regulates activity
PRKD1SIGNOR-275925
PKAphosphorylation
img/direct_inhibition.png
down-regulates
CAMKK2SIGNOR-198150
PKAphosphorylation

up-regulates activity
PHF2SIGNOR-264511
PKAphosphorylation

down-regulates activity
GRK7SIGNOR-274080
PKAphosphorylation

down-regulates activity
KCNK18SIGNOR-263154
PKAphosphorylation

up-regulates activity
SLC8B1SIGNOR-275728
PKAphosphorylation

up-regulates activity
GRK7SIGNOR-263152
PKAphosphorylation

up-regulates activity
ENAHSIGNOR-268285
PKAphosphorylation

up-regulates activity
SCN5ASIGNOR-275991
PKAphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
PPM1BSIGNOR-277825
PKAphosphorylation

up-regulates activity
PDE4CSIGNOR-273938
PKAphosphorylation

up-regulates activity
VASPSIGNOR-268286