| Name | PTK6_Tyr315 |
| ID | SIGNOR-PF24 |
| Role | residue |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RET | AKT | Tyr315 | TFCGTPEyLAPEVLE | phosphorylation up-regulates | 15994200 | SIGNOR-166514 |
| PTK6 | AKT | Tyr315 | TFCGTPEyLAPEVLE | phosphorylation up-regulates | 20606012 | SIGNOR-166506 |
| SRC | AKT | Tyr315 | TFCGTPEyLAPEVLE | phosphorylation up-regulates activity | 11445557 | SIGNOR-246368 |
| PTK6 | AKT | Tyr315 | TFCGTPEyLAPEVLE | phosphorylation up-regulates | 15994200 | SIGNOR-138437 |
| SRC | AKT | Tyr315 | TFCGTPEyLAPEVLE | phosphorylation up-regulates activity | 12600984 | SIGNOR-246373 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RET | phosphorylation up-regulates → | AKT PTyr315 | phosphorylation up-regulates → | AKT | 15994200 | SIGNOR-166514 |
| PTK6 | phosphorylation up-regulates → | AKT PTyr315 | phosphorylation up-regulates → | AKT | 20606012 | SIGNOR-166506 |
| SRC | phosphorylation up-regulates → | AKT PTyr315 | phosphorylation up-regulates → | AKT | 11445557 | SIGNOR-246368 |
| PTK6 | phosphorylation up-regulates → | AKT PTyr315 | phosphorylation up-regulates → | AKT | 15994200 | SIGNOR-138437 |
| SRC | phosphorylation up-regulates → | AKT PTyr315 | phosphorylation up-regulates → | AKT | 12600984 | SIGNOR-246373 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RET | phosphorylation → up-regulates | AKT | SIGNOR-166514 |
| PTK6 | phosphorylation → up-regulates | AKT | SIGNOR-166506 |
| SRC | phosphorylation → up-regulates activity | AKT | SIGNOR-246368 |
| PTK6 | phosphorylation → up-regulates | AKT | SIGNOR-138437 |
| SRC | phosphorylation → up-regulates activity | AKT | SIGNOR-246373 |