Entity Details

Name mTORC2_Ser477
ID SIGNOR-PF24
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
mTORC2AKTSer477PQFSYSAsGTAphosphorylation
up-regulates activity		24670654SIGNOR-252451
CyclinA2/CDK2AKTSer477PQFSYSAsGTAphosphorylation
up-regulates activity		24670654SIGNOR-252450
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
mTORC2phosphorylation
up-regulates
→
AKT
PSer477		phosphorylation
up-regulates
→		AKT24670654SIGNOR-252451
CyclinA2/CDK2phosphorylation
up-regulates
→
AKT
PSer477		phosphorylation
up-regulates
→		AKT24670654SIGNOR-252450
Regulator Mechanism/Effect Target SIGNOR-ID
mTORC2phosphorylation
→
up-regulates activity 		AKTSIGNOR-252451
CyclinA2/CDK2phosphorylation
→
up-regulates activity 		AKTSIGNOR-252450