Entity Details

Name ERK1/2_Thr573
ID SIGNOR-PF26
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1RPS6KThr573AENGLLMtPCYTANFphosphorylation
up-regulates activity		9430688SIGNOR-252752
MAPK3RPS6KThr573AENGLLMtPCYTANFphosphorylation
up-regulates activity		9430688SIGNOR-252757
MAPK1RPS6KThr573AENGLLMtPCYTANFphosphorylation
up-regulates activity		9687510SIGNOR-252753
ERK1/2RPS6KThr573AENGLLMtPCYTANFphosphorylation
up-regulates activity		9430688SIGNOR-252743
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
RPS6K
PThr573		phosphorylation
up-regulates
→		RPS6K9430688SIGNOR-252752
MAPK3phosphorylation
up-regulates
→
RPS6K
PThr573		phosphorylation
up-regulates
→		RPS6K9430688SIGNOR-252757
MAPK1phosphorylation
up-regulates
→
RPS6K
PThr573		phosphorylation
up-regulates
→		RPS6K9687510SIGNOR-252753
ERK1/2phosphorylation
up-regulates
→
RPS6K
PThr573		phosphorylation
up-regulates
→		RPS6K9430688SIGNOR-252743
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
up-regulates activity 		RPS6KSIGNOR-252752
MAPK3phosphorylation
→
up-regulates activity 		RPS6KSIGNOR-252757
MAPK1phosphorylation
→
up-regulates activity 		RPS6KSIGNOR-252753
ERK1/2phosphorylation
→
up-regulates activity 		RPS6KSIGNOR-252743