| Name | mTORC1_Thr390 |
| ID | SIGNOR-PF26 |
| Role | residue |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | RPS6K | Thr390 | DSKFTRQtPVDSPDD | phosphorylation up-regulates activity | 11914378 | SIGNOR-255841 |
| mTORC1 | RPS6K | Thr390 | DSKFTRQtPVDSPDD | phosphorylation up-regulates activity | 11914378 | SIGNOR-255842 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | phosphorylation up-regulates → | RPS6K PThr390 | phosphorylation up-regulates → | RPS6K | 11914378 | SIGNOR-255841 |
| mTORC1 | phosphorylation up-regulates → | RPS6K PThr390 | phosphorylation up-regulates → | RPS6K | 11914378 | SIGNOR-255842 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MTOR | phosphorylation → up-regulates activity | RPS6K | SIGNOR-255841 |
| mTORC1 | phosphorylation → up-regulates activity | RPS6K | SIGNOR-255842 |