Entity Details

Name NOTCH
ID SIGNOR-PF30
Role substrate
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK8NOTCH–phosphorylation
down-regulates		15546612SIGNOR-254312
CCNCNOTCH–phosphorylation
down-regulates		15546612SIGNOR-254309
DYRK1ANOTCH–phosphorylation
down-regulates		19383720SIGNOR-254313
CKM complexNOTCH–phosphorylation
down-regulates quantity by destabilization		15546612SIGNOR-273153
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
Regulator Mechanism/Effect Target SIGNOR-ID
CDK8phosphorylation
img/direct_inhibition.png
down-regulates 		NOTCHSIGNOR-254312
CCNCphosphorylation
img/direct_inhibition.png
down-regulates 		NOTCHSIGNOR-254309
DYRK1Aphosphorylation
img/direct_inhibition.png
down-regulates 		NOTCHSIGNOR-254313
CKM complexphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		NOTCHSIGNOR-273153