Entity Details

Name STK3/4
ID SIGNOR-PF41
Role kinase
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
STK3/4LATS1–phosphorylation
up-regulates		15688006SIGNOR-270217
STK3/4ABL1–phosphorylation
down-regulates		18794806SIGNOR-270219
STK3/4MOB1B–phosphorylation
up-regulates		21808241SIGNOR-270221
STK3/4MAP1LC3BThr50QLPVLDKtKFLVPDHphosphorylation
down-regulates activity		31857374SIGNOR-273905
STK3/4SAV1–phosphorylation
up-regulates activity		21084559SIGNOR-256184
STK3/4MOB1A–phosphorylation
up-regulates		18362890SIGNOR-270220
STK3/4LATS2–phosphorylation
up-regulates		21808241SIGNOR-270218
STK3/4Mob1–phosphorylation
up-regulates activity		23431053SIGNOR-256185
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
STK3/4phosphorylation
up-regulates
→
MAP1LC3B
PThr50		phosphorylation
down-regulates
⊣		MAP1LC3B31857374SIGNOR-273905
Regulator Mechanism/Effect Target SIGNOR-ID
STK3/4phosphorylation
→
up-regulates 		LATS1SIGNOR-270217
STK3/4phosphorylation
img/direct_inhibition.png
down-regulates 		ABL1SIGNOR-270219
STK3/4phosphorylation
→
up-regulates 		MOB1BSIGNOR-270221
STK3/4phosphorylation
→
down-regulates activity 		MAP1LC3BSIGNOR-273905
STK3/4phosphorylation
→
up-regulates activity 		SAV1SIGNOR-256184
STK3/4phosphorylation
→
up-regulates 		MOB1ASIGNOR-270220
STK3/4phosphorylation
→
up-regulates 		LATS2SIGNOR-270218
STK3/4phosphorylation
→
up-regulates activity 		Mob1SIGNOR-256185