| Name | STK3/4 |
| ID | SIGNOR-PF41 |
| Role | substrate |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT2 | STK3/4 | – | phosphorylation down-regulates | 20231902 | SIGNOR-269937 | |
| ABL1 | STK3/4 | – | phosphorylation up-regulates | 22590567 | SIGNOR-269946 | |
| TAOK3 | STK3/4 | – | phosphorylation up-regulates | 23431053 | SIGNOR-269949 | |
| TAOK | STK3/4 | – | phosphorylation up-regulates activity | 23431053 | SIGNOR-256182 | |
| TAOK2 | STK3/4 | – | phosphorylation up-regulates | 23431053 | SIGNOR-269939 | |
| PPP2CA | STK3/4 | – | dephosphorylation down-regulates | 23431053 | SIGNOR-269940 | |
| TAOK1 | STK3/4 | – | phosphorylation up-regulates | 23431053 | SIGNOR-269938 | |
| AKT | STK3/4 | – | phosphorylation down-regulates | 20086174 | SIGNOR-269944 | |
| AKT1 | STK3/4 | – | phosphorylation down-regulates | 20086174 | SIGNOR-269945 | |
| AKT3 | STK3/4 | – | phosphorylation down-regulates | 20231902 | SIGNOR-269941 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT2 | phosphorylation down-regulates | STK3/4 | SIGNOR-269937 |
| ABL1 | phosphorylation → up-regulates | STK3/4 | SIGNOR-269946 |
| TAOK3 | phosphorylation → up-regulates | STK3/4 | SIGNOR-269949 |
| TAOK | phosphorylation → up-regulates activity | STK3/4 | SIGNOR-256182 |
| TAOK2 | phosphorylation → up-regulates | STK3/4 | SIGNOR-269939 |
| PPP2CA | dephosphorylation down-regulates | STK3/4 | SIGNOR-269940 |
| TAOK1 | phosphorylation → up-regulates | STK3/4 | SIGNOR-269938 |
| AKT | phosphorylation down-regulates | STK3/4 | SIGNOR-269944 |
| AKT1 | phosphorylation down-regulates | STK3/4 | SIGNOR-269945 |
| AKT3 | phosphorylation down-regulates | STK3/4 | SIGNOR-269941 |