| Name | PK |
| ID | SIGNOR-PF80 |
| Role | kinase |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PK | STAT3 | Tyr705 | DPGSAAPyLKTKFIC | phosphorylation up-regulates | 22306293 | SIGNOR-268152 |
| PK | STAT3 | – | phosphorylation up-regulates activity | 22306293 | SIGNOR-270312 | |
| PK | STAT3 | – | phosphorylation up-regulates activity | 22306293 | SIGNOR-268149 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PK | phosphorylation up-regulates → | STAT3 PTyr705 | phosphorylation up-regulates → | STAT3 | 22306293 | SIGNOR-268152 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PK | phosphorylation → up-regulates | STAT3 | SIGNOR-268152 |
| PK | phosphorylation → up-regulates activity | STAT3 | SIGNOR-270312 |
| PK | phosphorylation → up-regulates activity | STAT3 | SIGNOR-268149 |