3.0
Summary
| Name |  sapitinib
|
| Synonyms | 2-[4-({4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)piperidin-1-yl]-N-methylacetamide (ChemIDplus), AZD-8931 (ChemIDplus), AZD8931 (ChemIDplus), sapitinib (WHO MedNet), sapitinib (ChemIDplus), sapitinib (WHO MedNet), sapitinibum (WHO MedNet) |
| IUPAC | 2-(4-{[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxy}piperidin-1-yl)-N-methylacetamide |
| Formula | C23H25ClFN5O3 |
| PRIMARY ID (Read more) |
CHEBI:132986 |
| Type | chemical |
| Relations | 7 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | sapitinib | down-regulates 
chemical inhibition
|
ERBB3 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | sapitinib | down-regulates
chemical inhibition
|
SHC3 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | sapitinib | down-regulates
chemical inhibition
|
ErbB receptor family | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | sapitinib | down-regulates
chemical inhibition
|
EGFR | 0.8 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | sapitinib | down-regulates
chemical inhibition
|
ERBB2 | 0.8 |
| Publications: | 2 | Organism: | Homo Sapiens | |