| + |
(R)-adrenaline | up-regulates 
|
LATS2 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-199199 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23075495 |
On the other hand, galfas-coupled signals, such as epinephrine and glucagon, induce kinase activity of lats1/2, leading to phosphorylation and yap/taz. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
(R)-adrenaline | up-regulates 
chemical activation
|
ADRB2 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-198501 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 22863277 |
In contrast, stimulation of gs-coupled receptors by glucagon or epinephrine activates lats1/2 kinase activity, thereby inhibiting yap function. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MAOB | up-regulates quantity
chemical modification
|
(R)-adrenaline |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269746 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20493079 |
The selective monoamine oxidase inhibitors clorgyline and (−)-deprenyl were used to study the distribution of monoamine oxidase-A and -B (MAO-A, MAO-B) activities towards (−)-noradrenaline and (+),(−)-adrenaline in homogenates from seven different regions of human brain. Noradreanline and adrenaline were substrates for both forms of the enzyme in all regions studied. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Brain |
| + |
(R)-adrenaline | up-regulates
|
LATS1/2 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269867 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23075495 |
On the other hand, galfas-coupled signals, such as epinephrine and glucagon, induce kinase activity of lats1/2, leading to phosphorylation and yap/taz. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
(R)-adrenaline | up-regulates
|
LATS1 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-199196 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23075495 |
On the other hand, galfas-coupled signals, such as epinephrine and glucagon, induce kinase activity of lats1/2, leading to phosphorylation and yap/taz. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MAOA | up-regulates quantity
chemical modification
|
(R)-adrenaline |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269744 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20493079 |
The selective monoamine oxidase inhibitors clorgyline and (−)-deprenyl were used to study the distribution of monoamine oxidase-A and -B (MAO-A, MAO-B) activities towards (−)-noradrenaline and (+),(−)-adrenaline in homogenates from seven different regions of human brain. Noradreanline and adrenaline were substrates for both forms of the enzyme in all regions studied. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Brain |
| + |
(R)-adrenaline | up-regulates activity
chemical activation
|
ADRA1A |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-258458 |
|
|
Cricetulus griseus |
CHO Cell |
| pmid |
sentence |
| 7651358 |
Membrane preparations from CHO cells stably transfected with the cloned human a1-AR genes showed saturable binding of [‘251]HEAT; Bm,,ı values were 1.3 ± 0.2, 5.5 ± 0.1, and 1.1 ± 0.1 pmol/mg of protein, with Kd values of 110 ± 21, 60 ± 1, and 300 ± 26 ıM (three experiments each), for the ala-, alb-, and ald-ARS, respectively. The potencies of a1-AR agonists and antagonists at the cloned human a1-ARs are shown in Table 1. |
|
| Publications: |
1 |
Organism: |
Cricetulus Griseus |
| + |
(R)-adrenaline | up-regulates activity
chemical activation
|
ADRA1D |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-258459 |
|
|
Cricetulus griseus |
CHO Cell |
| pmid |
sentence |
| 7651358 |
Membrane preparations from CHO cells stably transfected with the cloned human a1-AR genes showed saturable binding of [‘251]HEAT; Bm,,ı values were 1.3 ± 0.2, 5.5 ± 0.1, and 1.1 ± 0.1 pmol/mg of protein, with Kd values of 110 ± 21, 60 ± 1, and 300 ± 26 ıM (three experiments each), for the ala-, alb-, and ald-ARS, respectively. The potencies of a1-AR agonists and antagonists at the cloned human a1-ARs are shown in Table 1. |
|
| Publications: |
1 |
Organism: |
Cricetulus Griseus |
| + |
(R)-adrenaline | up-regulates activity
chemical activation
|
ADRA1B |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-258443 |
|
|
Cricetulus griseus |
|
| pmid |
sentence |
| 7651358 |
Membrane preparations from CHO cells stably transfected with the cloned human a1-AR genes showed saturable binding of [‘251]HEAT; Bm,,ı values were 1.3 ± 0.2, 5.5 ± 0.1, and 1.1 ± 0.1 pmol/mg of protein, with Kd values of 110 ± 21, 60 ± 1, and 300 ± 26 ıM (three experiments each), for the ala-, alb-, and ald-ARS, respectively. The potencies of a1-AR agonists and antagonists at the cloned human a1-ARs are shown in Table 1. |
|
| Publications: |
1 |
Organism: |
Cricetulus Griseus |
3.0
(R)-adrenaline