3.0
Summary
| Name |  lovastatin
|
| Synonyms | (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate (ChemIDplus), 2beta,6alpha-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone (ChemIDplus), 6alpha-methylcompactin (ChemIDplus), Lovastatin (KEGG COMPOUND), LOVASTATIN (PDBeChem), Mevacor (ChemIDplus), Mevinolin (ChemIDplus), MK-803 (KEGG DRUG), ML-530B (KEGG DRUG) |
| IUPAC | (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate |
| Formula | C24H36O5 |
| PRIMARY ID (Read more) |
CHEBI:40303 |
| Type | chemical |
| Relations | 3 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | lovastatin | up-regulates activity 
chemical activation
|
NR1I2 | 0.8 |
| Publications: | 1 | Organism: | Chlorocebus Aethiops | |
| + | lovastatin | down-regulates activity 
chemical inhibition
|
HMGCR | 0.8 |
| Publications: | 2 | Organism: | In Vitro | |