| + |
UNII-XH2662798I | down-regulates 
chemical inhibition
|
CDK1 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-163127 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20068082 |
Cdk1/cdc2 activation involves tyr15/thr14 dephosphorylation, regulated by wee1- and myt1-mediated phosphorylation and cdc25c-mediated dephosphorylation. Cdc25a may also be involved in cdk1 dephosphorylation in the g2/m-phase checkpoint. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UNII-XH2662798I | down-regulates 
|
Histone H3 |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265352 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20068082 |
Pf-00477736 also significantly enhances docetaxel efficacy in vitro and in vivo, in association with decreased cdc25c cytoplasmic phosphorylation (ser216) and histone h3 phosphorylation (ser10)(42). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UNII-XH2662798I | down-regulates
|
H3-3A |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-163130 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 20068082 |
Pf-00477736 also significantly enhances docetaxel efficacy in vitro and in vivo, in association with decreased cdc25c cytoplasmic phosphorylation (ser216) and histone h3 phosphorylation (ser10)(42). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
UNII-XH2662798I