3.0
Summary
| Name |  Ruxolitinib
|
| Synonyms | 941678-49-5, INCB-018424, INCB018424 |
| IUPAC | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile |
| Formula | C17H18N6 |
| PRIMARY ID (Read more) |
CHEBI:66919 |
| PubChem ID | CID:25126798 |
| Type | chemical |
| Relations | 6 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | Ruxolitinib | down-regulates 
chemical inhibition
|
JAK2 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Ruxolitinib | down-regulates activity
chemical inhibition
|
JAK1 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Ruxolitinib | down-regulates
chemical inhibition
|
JAK1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Ruxolitinib | down-regulates activity
chemical inhibition
|
JAK3 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Ruxolitinib | down-regulates
chemical inhibition
|
JAK3 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Ruxolitinib | down-regulates activity
chemical inhibition
|
JAK2 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |