+ |
budesonide | up-regulates
chemical activation
|
NR3C1 |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-251690 |
|
|
Homo sapiens |
|
pmid |
sentence |
9753485 |
|
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-251687 |
|
|
Homo sapiens |
|
pmid |
sentence |
11208622 |
|
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-251689 |
|
|
Homo sapiens |
|
pmid |
sentence |
9657565 |
|
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-251688 |
|
|
Homo sapiens |
|
pmid |
sentence |
6958488 |
|
|
Publications: |
4 |
Organism: |
Homo Sapiens |
Pathways: | Glucocorticoid receptor Signaling |
+ |
budesonide | up-regulates activity
chemical activation
|
NR3C1 |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-253053 |
|
|
in vitro |
|
pmid |
sentence |
9793625 |
Mometasone furoate (MF, CAS 83919-23-7, Sch 32088), budesonide (BUD, CAS 51372-29-3), fluticasone propionate (FP, CAS 80474-14-2), and triamcinolone acetonide (TA, CAS-76-25-5) are corticosteroids. All of the test compounds had a higher affinity for the recombinant glucocorticoid receptor than the reference glucocorticoid receptor ligand, dexamethasone (DEX, CAS 50-02-2). All compounds showed greater potency than dexamethasone in stimulating transcription of a synthetic target gene regulated by a glucocorticoid response element. |
|
Publications: |
1 |
Organism: |
In Vitro |
Pathways: | Glucocorticoid receptor Signaling |