3.0
Summary
| Name |  Nintedanib
|
| Synonyms | BIBF-1120, Vargatef, BIBF1120 |
| IUPAC | methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate |
| Formula | C31H33N5O4 |
| PRIMARY ID (Read more) |
CHEBI:85164 |
| PubChem ID | CID:9809715 |
| Type | chemical |
| Relations | 12 |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | Nintedanib | down-regulates activity 
chemical inhibition
|
PDGFRA | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Nintedanib | down-regulates activity
chemical inhibition
|
KDR | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Nintedanib | down-regulates activity
chemical inhibition
|
FGFR2 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Nintedanib | down-regulates activity
chemical inhibition
|
FGFR4 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Nintedanib | down-regulates activity
chemical inhibition
|
PDGFRB | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Nintedanib | down-regulates activity
chemical inhibition
|
FGFR3 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Nintedanib | down-regulates activity
chemical inhibition
|
FLT4 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Nintedanib | down-regulates
chemical inhibition
|
FLT1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Nintedanib | down-regulates activity
chemical inhibition
|
FLT1 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |
| + | Nintedanib | down-regulates
chemical inhibition
|
KDR | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Nintedanib | down-regulates
chemical inhibition
|
FLT4 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | Nintedanib | down-regulates activity
chemical inhibition
|
FGFR1 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |