3.0
Summary
| Name |  HPNView Modifications |
| Full Name | Serine protease hepsin |
| Synonyms | Transmembrane protease serine 1 | TMPRSS1 |
| Primary ID | P05981 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL (PubMed:21875933, PubMed:15839837). Plays a role in cell growth and maintenance of cell morphology (PubMed:8346233, PubMed:21875933). Plays a role in the proteolytic processing of ACE2 (PubMed:24227843). Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization (PubMed:26673890). |
cleavage