Summary

Name SPRR1B
Full Name Cornifin-B
Synonyms 14.9 kDa pancornulin, Small proline-rich protein IB, SPR-IB |
Primary ID P22528
Links - -
Type protein
Relations 2
Function Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation SPRR1B 0.242
Publications: 1
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation SPRR1B 0.2
Publications: 1