Summary

Name PON1
Full Name Serum paraoxonase/arylesterase 1
Synonyms PON 1, Aromatic esterase 1, A-esterase 1, K-45, Serum aryldialkylphosphatase 1 | PON
Primary ID P27169
Links - -
Type protein
Relations 2
Function Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.

Viewer

Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation PON1 0.304
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation PON1 0.273
Publications: 1 Organism: Homo Sapiens