Summary

Name GDNF
Full Name Glial cell line-derived neurotrophic factor
Synonyms hGDNF, Astrocyte-derived trophic factor, ATF
Primary ID P39905
Links - -
Type protein
Relations 24
Function Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Viewer

Relations

Regulator Mechanism target score
+ up-regulates img/indirect-activation.png unknown Neural tissue regeneration
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation PAFAH1B1
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation DCX
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation DNM2
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation TUBA1A
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates activity img/direct-activation.png binding NCAM1
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates img/direct-activation.png binding GFRA2 0.64
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GFRA1 0.97
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ up-regulates img/direct-activation.png binding RET 0.88
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation LAMA3 0.07
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MAP1LC3B 0.08
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation ALCAM 0.07
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation BIN1 0.08
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation ID1 0.07
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation ID2 0.07
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation ID3 0.11
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation NRG1 0.11
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation NRN1 0.13
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation PTK2 0.03
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation RHOQ 0.09
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation PDPK1 0.06
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CLU 0.05
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation FST 0.06
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates activity img/indirect-activation.png unknown GCH1 0.09
Publications: 1 Organism: Homo Sapiens