3.0
Summary
| Name |  CX3CR1
|
| Full Name | CX3C chemokine receptor 1 |
| Synonyms | C-X3-C CKR-1, CX3CR1, Beta chemokine receptor-like 1, CMK-BRL-1, CMK-BRL1, Fractalkine receptor, G-protein coupled receptor 13, V28 | CMKBRL1, GPR13 |
| Primary ID | P49238 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions (PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1 (PubMed:14607932). |
binding