| + |
SP4 | up-regulates quantity by expression 
transcriptional regulation
|
MAOB |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253869 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11259630 |
Cotransfection experiments show that Sp1 and its closely related family member Sp4 can trans-activate MAO B promoter activity through the proximal cluster of Sp1 sites and its activation can be repressed by the over-expression of Sp3 and a related family member BTEB2. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SP4 | up-regulates activity 
binding
|
CRX |
0.397 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-225333 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15781457 |
Sp4 directly binds Crx. Sp4 and Sp1 produce much higher levels of transcriptional activation when co-transfected with Crx, they may additionally act by directly increasing the rate of transcriptional initiation by the general transcriptional apparatus through their activation domains. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SP4 | up-regulates quantity by expression
transcriptional regulation
|
RHO |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-225382 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 15781457 |
Sp4 and Sp1 are activators of the rod opsin promoter |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
SP4
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