3.0
Summary
| Name |  SPDYA
|
| Full Name | Speedy protein A |
| Synonyms | Rapid inducer of G2/M progression in oocytes A, RINGO A, hSpy/Ringo A, Speedy-1, Spy1 | SPDY1, SPY1 |
| Primary ID | Q5MJ70 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2 (PubMed:12972555). Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation (PubMed:28666995). Mediates cell survival during the DNA damage process through activation of CDK2 (PubMed:12839962). |
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relocalization