| + |
FASTKD5 | up-regulates quantity by expression 
transcriptional regulation
|
COX4I1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261223 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25683715 |
FASTKD5 is required for maturing precursor mRNAs that are not flanked by tRNAs and that therefore cannot be processed by the canonical mRNA maturation pathway. Silencing FASTKD5 rendered mature COX I mRNA almost undetectable, which severely reduced the synthesis of COX I, resulting in a complex IV assembly defect. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
GRSF1 | down-regulates quantity by repression 
transcriptional regulation
|
FASTKD5 |
0.383 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261224 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25683715 |
DHX30 siRNA treatment resulted in an increase of FASTKD2 levels, and FASTKD5 was increased in cells treated with siRNA for GRSF1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FASTKD5 | up-regulates
|
Stress_granules |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261226 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25683715 |
DHX30, DDX28, FASTKD2, and FASTKD5 Are Bona Fide RNA Granule Proteins. FASTKD5 siRNA treatment caused a reduction of all RNA granule proteins, along with MRPS18B, a protein of the mt-SSU. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
FASTKD5
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