Summary

Name PIGK
Full Name GPI-anchor transamidase
Synonyms GPI transamidase, GPI8 homolog, hGPI8, Phosphatidylinositol-glycan biosynthesis class K protein, PIG-K | GPI8
Primary ID Q92643
Links - -
Type protein
Relations 1
Function Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

Viewer

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding PIGK 0.94
Publications: 1 Organism: Mus Musculus