Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260637 |
|
|
Homo sapiens |
Hep-G2 Cell |
pmid |
sentence |
15308636 |
Among novel cycling proteins we have characterized ERGIC-32, a new ERGIC protein that interacts with human Erv46, a protein previously characterized in yeast and functioning in ER to Golgi protein trafficking. ERGIC-32 interacts with human Erv46 (hErv46) as revealed by covalent cross-linking and mistargeting experiments, and silencing of ERGIC-32 by small interfering RNAs increases the turnover of hErv46. We propose that ERGIC-32 functions as a modulator of the hErv41-hErv46 complex by stabilizing hErv46. |
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