3.0
Summary
| Name |  FAM162A
|
| Full Name | Protein FAM162A |
| Synonyms | E2-induced gene 5 protein, Growth and transformation-dependent protein, HGTD-P | C3orf28, E2IG5 |
| Primary ID | Q96A26 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues (PubMed:15082785). May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition (PubMed:15082785). May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly (By similarity). |
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transcriptional regulation