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Summary
Name
VCPKMT
Full Name
Protein-lysine methyltransferase METTL21D
Synonyms
Methyltransferase-like protein 21D, VCP lysine methyltransferase, VCP-KMT, Valosin-containing protein lysine methyltransferase | C14orf138, METTL21D
Primary ID
Q9H867
Links
-
-
Type
protein
Relations
1
Function
Protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity.
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by mechanism
none
binding
by effect
none
up-regulates
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
Relations
Regulator
Mechanism
target
score
ℹ
+
ASPSCR1
up-regulates
binding
VCPKMT
0.352
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-200572
Homo sapiens
pmid
sentence
23349634
In the case of vcp, methylation by mettl21d was stimulated by the addition of the ubx cofactor aspscr1, which we show directly interacts with the methyltransferase.
Publications:
1
Organism:
Homo Sapiens