Summary

Name ZFYVE1
Full Name Zinc finger FYVE domain-containing protein 1
Synonyms Double FYVE-containing protein 1, SR3, Tandem FYVE fingers-1 | DFCP1, KIAA1589, TAFF1, ZNFN2A1
Primary ID Q9HBF4
Links - -
Type protein
Relations 1
Function Plays a role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (PubMed:30970241). Regulates the morphology, size and distribution of LDs (PubMed:31293035, PubMed:30970241). Mediates the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts by forming a complex with RAB18 and ZW10 (PubMed:30970241). Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through FYVE-type zinc finger (PubMed:11739631, PubMed:11256955).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png chemical activation ZFYVE1 0.8
Publications: 1 Organism: Homo Sapiens