| + |
ZMIZ1 | up-regulates activity 
binding
|
AR |
0.697 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263935 |
|
|
Homo sapiens |
LNCaP Cell |
| pmid |
sentence |
| 14609956 |
Our results demonstrate that hZimp10 is a novel AR interacting protein that augments AR-mediated transcription. Moreover, hZimp10 co-localized with AR and SUMO-1 at replication foci throughout S phase, and it was capable of enhancing sumoylation of AR in vivo. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ZMIZ1 | up-regulates 
|
Chromatine_condensation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263938 |
|
|
Mus musculus |
T-cell Lymphoma Cell |
| pmid |
sentence |
| 26522984 |
Our data suggest that Zmiz1 and Notch1 cooperatively recruit each other to chromatin through direct interaction via the TPR resulting in a slight increase in activating histone marks and decrease of repressive histone marks. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
ZMIZ1 | up-regulates quantity by expression
transcriptional regulation
|
MYC |
0.375 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263939 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 26522984 |
The N-terminal domain (NTD) of Zmiz1 is important for driving Myc transcription and proliferation […] Zmiz1 directly interacted with Notch1 via a tetratricopeptide repeat domain at a special class of Notch-regulatory sites. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
NOTCH1 | up-regulates activity
binding
|
ZMIZ1 |
0.467 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263937 |
|
|
Mus musculus |
T-cell Lymphoma Cell |
| pmid |
sentence |
| 26522984 |
The N-terminal domain (NTD) is critical for Zmiz1 to function as a Notch collaborator. Zmiz1 and Notch1 cooperatively recruit each other to chromatin through the TPR domain. The N-terminal domain (NTD) of Zmiz1 is important for enhancing Notch reporter activity and contains tetratricopeptide repeats (TPR) that mediate protein-protein interactions |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
ZMIZ1 | up-regulates activity
binding
|
NOTCH1 |
0.467 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263936 |
|
|
Mus musculus |
T-cell Lymphoma Cell |
| pmid |
sentence |
| 26522984 |
The N-terminal domain (NTD) is critical for Zmiz1 to function as a Notch collaborator. Zmiz1 and Notch1 cooperatively recruit each other to chromatin through the TPR domain. The N-terminal domain (NTD) of Zmiz1 is important for enhancing Notch reporter activity and contains tetratricopeptide repeats (TPR) that mediate protein-protein interactions |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
ZMIZ1
- 
- 