Summary

Name NR2E3
Full Name Photoreceptor-specific nuclear receptor
Synonyms Nuclear receptor subfamily 2 group E member 3, Retina-specific nuclear receptor | PNR, RNR
Primary ID Q9Y5X4
Links - -
Type protein
Relations 3
Function Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.

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Relations

Regulator Mechanism target score
+ up-regulates img/indirect-activation.png NR2E3 0.41
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding NR1D1 0.41
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation ESR1 0.255
Publications: 1 Organism: Homo Sapiens