3.0
Summary
| Name |  RFNG
|
| Full Name | Beta-1,3-N-acetylglucosaminyltransferase radical fringe |
| Synonyms | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| Primary ID | Q9Y644 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in enhancement of NOTCH1 activation by DLL1 and JAG1. May be involved in limb formation and in neurogenesis. |
binding