| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK13 | EEF2K | Ser359 | GTEEKCGsPQVRTLS | phosphorylation down-regulates | 18337751 | SIGNOR-177986 |
| CDK1 | EEF2K | Ser359 | GTEEKCGsPQVRTLS | phosphorylation down-regulates | 18337751 | SIGNOR-177982 |
| MAPK13 | EEF2K | Ser359 | GTEEKCGsPQVRTLS | phosphorylation down-regulates activity | 11500363 | SIGNOR-109703 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK13 | phosphorylation up-regulates → | EEF2K PSer359 | phosphorylation down-regulates ⊣ | EEF2K | 18337751 | SIGNOR-177986 |
| CDK1 | phosphorylation up-regulates → | EEF2K PSer359 | phosphorylation down-regulates ⊣ | EEF2K | 18337751 | SIGNOR-177982 |
| MAPK13 | phosphorylation up-regulates → | EEF2K PSer359 | phosphorylation down-regulates ⊣ | EEF2K | 11500363 | SIGNOR-109703 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK13 | phosphorylation![]() down-regulates | EEF2K | SIGNOR-177986 |
| CDK1 | phosphorylation![]() down-regulates | EEF2K | SIGNOR-177982 |
| MAPK13 | phosphorylation → down-regulates activity | EEF2K | SIGNOR-109703 |