Entity Details

Name PRKAA1_Ser78
ID O00418
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TRPM7EEF2KSer78SSGSPANsFHFKEAWphosphorylation
up-regulates activity		21112387SIGNOR-277923
PRKAA1EEF2KSer78SSGSPANsFHFKEAWphosphorylation
down-regulates activity		14709557SIGNOR-250314
PRKAA2EEF2KSer78SSGSPANsFHFKEAWphosphorylation
down-regulates activity		14709557SIGNOR-250321
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TRPM7phosphorylation
up-regulates
→
EEF2K
PSer78		phosphorylation
up-regulates
→		EEF2K21112387SIGNOR-277923
PRKAA1phosphorylation
up-regulates
→
EEF2K
PSer78		phosphorylation
down-regulates
⊣		EEF2K14709557SIGNOR-250314
PRKAA2phosphorylation
up-regulates
→
EEF2K
PSer78		phosphorylation
down-regulates
⊣		EEF2K14709557SIGNOR-250321
Regulator Mechanism/Effect Target SIGNOR-ID
TRPM7phosphorylation
→
up-regulates activity 		EEF2KSIGNOR-277923
PRKAA1phosphorylation
→
down-regulates activity 		EEF2KSIGNOR-250314
PRKAA2phosphorylation
→
down-regulates activity 		EEF2KSIGNOR-250321