| Name | KMT2D |
| ID | O14686 |
| Role | substrate |
| Enzymatic Domains |
FYR N-terminal 5175-5235 PROSITE-ProRule
FYR C-terminal 5236-5321 PROSITE-ProRule
SET 5397-5513 PROSITE-ProRule
Post-SET 5521-5537 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SGK1 | KMT2D | Ser1331 | RGRARLKsTASSIET | phosphorylation down-regulates activity | 30943409 | SIGNOR-277447 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SGK1 | phosphorylation up-regulates → | KMT2D PSer1331 | phosphorylation down-regulates ⊣ | KMT2D | 30943409 | SIGNOR-277447 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SGK1 | phosphorylation → down-regulates activity | KMT2D | SIGNOR-277447 |