| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SGK1 | KMT2D | Ser1331 | RGRARLKsTASSIET | phosphorylation down-regulates activity | 30943409 | SIGNOR-277447 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SGK1 | phosphorylation up-regulates → | KMT2D PSer1331 | phosphorylation down-regulates ⊣ | KMT2D | 30943409 | SIGNOR-277447 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SGK1 | phosphorylation → down-regulates activity | KMT2D | SIGNOR-277447 |