Entity Details

Name PRKACA_Thr288
ID O14965
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AURKAAURKAThr288APSSRRTtLCGTLDYphosphorylation
up-regulates		24867643SIGNOR-205106
PAK1AURKAThr288APSSRRTtLCGTLDYphosphorylation
up-regulates		24867643SIGNOR-205110
PRKACAAURKAThr288APSSRRTtLCGTLDYphosphorylation
up-regulates activity		11039908SIGNOR-250337
SRCAURKAThr288APSSRRTtLCGTLDYphosphorylation
up-regulates activity		25501815SIGNOR-279286
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AURKAphosphorylation
up-regulates
→
AURKA
PThr288		phosphorylation
up-regulates
→		AURKA24867643SIGNOR-205106
PAK1phosphorylation
up-regulates
→
AURKA
PThr288		phosphorylation
up-regulates
→		AURKA24867643SIGNOR-205110
PRKACAphosphorylation
up-regulates
→
AURKA
PThr288		phosphorylation
up-regulates
→		AURKA11039908SIGNOR-250337
SRCphosphorylation
up-regulates
→
AURKA
PThr288		phosphorylation
up-regulates
→		AURKA25501815SIGNOR-279286
Regulator Mechanism/Effect Target SIGNOR-ID
AURKAphosphorylation
→
up-regulates 		AURKASIGNOR-205106
PAK1phosphorylation
→
up-regulates 		AURKASIGNOR-205110
PRKACAphosphorylation
→
up-regulates activity 		AURKASIGNOR-250337
SRCphosphorylation
→
up-regulates activity 		AURKASIGNOR-279286