Entity Details

Name MAPK13
ID O15264
Role kinase
Enzymatic Domains
Protein kinase 25-308
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK13EEF2KSer359GTEEKCGsPQVRTLSphosphorylation
down-regulates
18337751SIGNOR-177986
MAPK13EEF2KSer359GTEEKCGsPQVRTLSphosphorylation
down-regulates activity
11500363SIGNOR-109703
MAPK13EEF2KSer396TFDSLPSsPSSATPHphosphorylation
down-regulates activity
11500363SIGNOR-250089
MAPK13TP53Ser33LPENNVLsPLPSQAMphosphorylation
up-regulates
10581258SIGNOR-72687
MAPK13TP53Ser46AMDDLMLsPDDIEQWphosphorylation
up-regulates
10581258SIGNOR-72691
MAPK13KRT8Ser74TVNQSLLsPLVLEVDphosphorylation
up-regulates
11788583SIGNOR-114075
MAPK13MAPTphosphorylation
down-regulates activity
9199504SIGNOR-278313
MAPK13STMN1Ser25QAFELILsPRSKESVphosphorylation
down-regulates
8125092SIGNOR-36362
MAPK13STMN1Ser25QAFELILsPRSKESVphosphorylation
down-regulates
8325880SIGNOR-37848
MAPK13STMN1Ser38SVPEFPLsPPKKKDLphosphorylation
down-regulates
8325880SIGNOR-25826
MAPK13TP53BP1Thr1609LGPYEAVtPLTKAADphosphorylation
down-regulates activity
24703952SIGNOR-264449
MAPK13PRKD1phosphorylation
down-regulates
19135240SIGNOR-183280
MAPK13RCSD1Ser68GQNGEEKsPPNASHPphosphorylation
down-regulates activity
15850461SIGNOR-263084
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK13phosphorylation
up-regulates
EEF2K
PSer359
phosphorylation
down-regulates
EEF2K18337751SIGNOR-177986
MAPK13phosphorylation
up-regulates
EEF2K
PSer359
phosphorylation
down-regulates
EEF2K11500363SIGNOR-109703
MAPK13phosphorylation
up-regulates
EEF2K
PSer396
phosphorylation
down-regulates
EEF2K11500363SIGNOR-250089
MAPK13phosphorylation
up-regulates
TP53
PSer33
phosphorylation
up-regulates
TP5310581258SIGNOR-72687
MAPK13phosphorylation
up-regulates
TP53
PSer46
phosphorylation
up-regulates
TP5310581258SIGNOR-72691
MAPK13phosphorylation
up-regulates
KRT8
PSer74
phosphorylation
up-regulates
KRT811788583SIGNOR-114075
MAPK13phosphorylation
up-regulates
STMN1
PSer25
phosphorylation
down-regulates
STMN18125092SIGNOR-36362
MAPK13phosphorylation
up-regulates
STMN1
PSer25
phosphorylation
down-regulates
STMN18325880SIGNOR-37848
MAPK13phosphorylation
up-regulates
STMN1
PSer38
phosphorylation
down-regulates
STMN18325880SIGNOR-25826
MAPK13phosphorylation
up-regulates
TP53BP1
PThr1609
phosphorylation
down-regulates
TP53BP124703952SIGNOR-264449
MAPK13phosphorylation
up-regulates
RCSD1
PSer68
phosphorylation
down-regulates
RCSD115850461SIGNOR-263084
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK13phosphorylation
img/direct_inhibition.png
down-regulates
EEF2KSIGNOR-177986
MAPK13phosphorylation

down-regulates activity
EEF2KSIGNOR-109703
MAPK13phosphorylation

down-regulates activity
EEF2KSIGNOR-250089
MAPK13phosphorylation

up-regulates
TP53SIGNOR-72687
MAPK13phosphorylation

up-regulates
TP53SIGNOR-72691
MAPK13phosphorylation

up-regulates
KRT8SIGNOR-114075
MAPK13phosphorylation

down-regulates activity
MAPTSIGNOR-278313
MAPK13phosphorylation
img/direct_inhibition.png
down-regulates
STMN1SIGNOR-36362
MAPK13phosphorylation
img/direct_inhibition.png
down-regulates
STMN1SIGNOR-37848
MAPK13phosphorylation
img/direct_inhibition.png
down-regulates
STMN1SIGNOR-25826
MAPK13phosphorylation

down-regulates activity
TP53BP1SIGNOR-264449
MAPK13phosphorylation
img/direct_inhibition.png
down-regulates
PRKD1SIGNOR-183280
MAPK13phosphorylation

down-regulates activity
RCSD1SIGNOR-263084