Entity Details

Name CDK1_Ser40
ID O15297
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1PPM1DSer40PTAEEKPsPRRSLSQphosphorylation
down-regulates quantity by destabilization		33309518SIGNOR-275489
CyclinB/CDK1PPM1DSer40PTAEEKPsPRRSLSQdephosphorylation
down-regulates quantity by destabilization		33309518SIGNOR-275490
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
PPM1D
PSer40		phosphorylation
down-regulates
⊣		PPM1D33309518SIGNOR-275489
CyclinB/CDK1dephosphorylation
down-regulates
⊣
PPM1D
PSer40		dephosphorylation
up-regulates
→		PPM1D33309518SIGNOR-275490
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		PPM1DSIGNOR-275489
CyclinB/CDK1dephosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		PPM1DSIGNOR-275490