| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK2 | TP73 | Ser48 | VVGGTDSsMDVFHLE | phosphorylation down-regulates activity | 26625870 | SIGNOR-278218 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK2 | phosphorylation up-regulates → | TP73 PSer48 | phosphorylation down-regulates ⊣ | TP73 | 26625870 | SIGNOR-278218 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK2 | phosphorylation → down-regulates activity | TP73 | SIGNOR-278218 |