Entity Details

Name FANCA
ID O15360
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AURKAFANCASer165HSMFSRLsFCQELWKphosphorylation
up-regulates activity
27398318SIGNOR-277263
ATRFANCASer1449AAPDADLsQEPHLFphosphorylation
up-regulates
19109555SIGNOR-182953
AKTFANCASer1149CLRSRDPsLMVDFILphosphorylation
unknown
11855836SIGNOR-251476
PRKAA1FANCASer347VQMQREWsFARTHPLphosphorylation
up-regulates activity
27449087SIGNOR-277264
AKT1FANCASer1149CLRSRDPsLMVDFILphosphorylation
unknown
11855836SIGNOR-252567
ATMFANCASer1449AAPDADLsQEPHLFphosphorylation
up-regulates
19109555SIGNOR-182949
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AURKAphosphorylation
up-regulates
FANCA
PSer165
phosphorylation
up-regulates
FANCA27398318SIGNOR-277263
ATRphosphorylation
up-regulates
FANCA
PSer1449
phosphorylation
up-regulates
FANCA19109555SIGNOR-182953
AKTphosphorylation
up-regulates
FANCA
PSer1149
phosphorylation
down-regulates
FANCA11855836SIGNOR-251476
PRKAA1phosphorylation
up-regulates
FANCA
PSer347
phosphorylation
up-regulates
FANCA27449087SIGNOR-277264
AKT1phosphorylation
up-regulates
FANCA
PSer1149
phosphorylation
down-regulates
FANCA11855836SIGNOR-252567
ATMphosphorylation
up-regulates
FANCA
PSer1449
phosphorylation
up-regulates
FANCA19109555SIGNOR-182949
Regulator Mechanism/Effect Target SIGNOR-ID
AURKAphosphorylation

up-regulates activity
FANCASIGNOR-277263
ATRphosphorylation

up-regulates
FANCASIGNOR-182953
AKTphosphorylation

unknown
FANCASIGNOR-251476
PRKAA1phosphorylation

up-regulates activity
FANCASIGNOR-277264
AKT1phosphorylation

unknown
FANCASIGNOR-252567
ATMphosphorylation

up-regulates
FANCASIGNOR-182949